E-Articles - Health and Fitness

WHY CONTACTS? The word is nearly as old as the mountains and a number of people still turn around and fire the '

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

why' thing at you. All you do is shrug your eyes spread wide in wonder if there could be such a question regardi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ng something that has been around for what seems like eternity now. But then, a question is a question howsoever

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

obvious the answer might be.

First and the foremost, one gets rid of the irritating apparatus on one's face, wh

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ich immediately undoes the aesthetic loss caused by its presence. In short, you look smarter than ever. That was

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

one reason that comes first to anyone who thinks about the pros of the contacts, but it is not the only one by a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ny means.

When was the last time you wished you had wipers on your glasses so that you didn't have to take them

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

off ever now and then to remove the misty presence of water or snow. That's another one of the advantages.

The

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

glasses distort the appearance of objects. This distortion is done away with in case of contacts. One sees the r

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

eal things the real way. Besides, the peripheral vision is, to a large extent, compromised with glasses, which i

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

not the case with the lenses.

For sportsmen who play outdoor games like football, lenses are indispensable bec

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ause with glasses chances are that one fine day while you are chasing the ball, it will suddenly disappear and

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

by the time you get your glasses back, the opponents will be celebrating. In short, get the lenses before you ar

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

out of the team.

Those were the pros, but it would be unfair to the 'why-guy' if we hid the downside. The most

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

prominent disadvantage is that they need careful handling and frequent replacements, which makes them delicate

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

things that are heavy on the pocket.

Another problem is that since contacts are worn inside the eyes, the chanc

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

es of infection are quite high. And for the carefree professionals there is an extra note of caution. Dear fel

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

low, unlike the glasses, you cannot just come home and toss them off. You need to clean them, disinfect them and

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

then place them back in the lens case.

Thus, time, diligence, patience and money are the four things a contact

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

lens demands of its wearer. If you have them, it's a great companion, and if not, better get used to the glasses

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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I began as the founder and CEO of EMJ, a computer distributing company that grew from zero to over $350,000,000 in sales. I sold EMJ to SYNNEX, and became the CEO of SYNNEX Canada, a company that does over $1 billion in sales. One thing I have learned through these years of experience is the power of questions.

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