E-Articles - Health and Fitness

Lasik stands for Laser-Assisted In Situ Keratomileusis and is a procedure that permanently changes the shape of the cornea, the clear coverin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g of the front of the eye, using an excimer laser. Lasik is a surgical procedure intended to reduce a person's dependency on glasses or conta

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ct lenses. If you are thinking about undergoing an eye surgery, think about Lasik eye surgery. Make sure you review all your options with an

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

experienced eye professional. Every type of surgery should be considered serious. You always should understand both the benefits and the risk

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s of the surgery.

Lasik surgery carefully removes the corneal tissue with a laser and this gentle laser then reshapes the cornea itself. Thi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s action in turn adjusts and strengthens the power your cornea has to focus on objects far and near. This type of surgery is more commonly kn

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

own as refractive surgery. There are many types of eye surgeries that can be performed today to increase your vision strength. The most commo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n other two types of surgery include, radial keratotomy and photorefractive keratectomy. These two surgeries are also aimed to reshape the co

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rnea, but using different techniques to do so.

Lasik surgery can be done with a laser or with a small knife. The radial keratotomy is the ty

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

pe of eye surgery that uses this small knife. The small knife is used to make several slits in the cornea these few small slits change the sh

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

pe and the focus of your cornea. These two types of surgery are very effective. Of course your eye will be incredibly sensitive following a s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

urgery of this kind, but this is to be expected. You may feel slight irritation concerning your eye as well. These irritations are mild and a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

simple pain reliever will ease your pain. These symptoms are only directly following your Lasik surgery.

Most patients are very pleased wit

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

h the results of their refractive surgery. However, like any other medical procedure, there are risks involved. That's why it is important fo

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

r you to understand the limitations and possible complications of refractive surgery.

If you decide to go ahead with Lasik surgery, you will

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

need an initial or baseline evaluation by your eye doctor to determine if you are a good candidate. If you wear contact lenses, it is a good

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

idea to stop wearing them before your baseline evaluation and switch to wearing your glasses full-time. Not leaving your contact lenses out

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

long enough for your cornea to assume its natural shape before surgery can have negative consequences. The consequences include inaccurate me

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

asurements and can lead to a poor surgical plan, resulting in poor vision after surgery. The measurements may need to be repeated at least a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

week after your first evaluation and before surgery to make sure they have not changed. This is very important if you wear RGP or hard lenses

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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