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If you are among the group of people who are both nearsighted and farsighted, the only option available to you is glasses with big, thick bifocal lenses. Frames like these are big and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

heavy, and don't generally complement the wearer's face. Bifocal lenses of the older type were hard to get used to. Fortunately, the latest bifocal contact lenses are much improved ov

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r the old.

In the older days, glasses used to be the only option. Bi focal lenses were the last to be developed. Fortunately things have come a long way since then. Today, there are

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

many more choices available. You never have to wear those big clunky frames anymore! You can now get a pair made of rigid, soft and gas permeable materials.

The cause for this need i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

called 'presbyopia.' It usually occurs after someone is 40 years old. Since wearers of such lenses are partly nearsighted and partly farsighted, they are designed so that half the le

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s can view up close and half the lens can see far away.

The way such lenses are made is called 'simultaneous design.' They have both circle powers, so that your pupils can adjust to w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hichever it needs, whether near or far away. There is another style though and this is called Concentric Design. With these lenses, the inner part is used to focus on what is close an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the outer part is for distance focusing.

With Translating Design, the contact lens has a line which divides it. The bottom of it is flat so that it won't move when you close your eye

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

.

The Asferic Design enable both near focusing and distance focusing. This is done in the same place.

Usually, the near vision prescription is located in the middle of the contact len

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

, and the prescription for focusing on distances is in the outer part of it. Depending on your situation, your eye doctor may prescribe the opposite. There is another kind of design w

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ere you actually wear a different prescription in each eye.

Usually, the dominant eye gets the far away vision. This will be determined by your doctor. You can also get the Simultane

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ous Vision type, where you can view both what's near as well as what's far at the same time.

Both corrections are controlled by concentric circles in the lens. It can use light from a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ywhere to focus on what is in front of the eyes.

The only problem with Simultaneous Vision is that light will sometimes bleed over from one correction to the other. This will cause th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

eye to have some trouble focusing, as it goes in and out of focus.

This puts the burden on your brain to decide which part of the eye to use. Leave it all up to your eye doctor. He

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ill be able to prescribe the right type of lens for you.

Like most other adjustments, it may take a while to find just the right one that is suitable and comfortable for you. Contact

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

enses are not for all, so it may not be a good idea for you to use a lens correction system. You should leave this decision to your doctor. He can give you the best advice on which to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

use.

It is wise to keep yourself informed on the newest developments. With many eye care or vision companies you can try a free trial to see if that particular brand and style suits y

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

u.

It should not be hard to find discounts on lenses if you look hard enough. Most lens companies want your business, so they will offer you coupons as well as other deals. So, keep

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

earching until you find lenses that are affordable as well as suitable. See if you can find others who have tried these and ask for their opinion. You might be able to get some good

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

dvice by searching the internet and look at websites and forums. What you also can find is various kinds of clinical lenses, for example lenses for astigmatism if that is what you need

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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