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There are many types of contact lenses, and choosing the one that you like best can be

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a bit challenging. The different types of lenses carry different sets of advantages, so

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you might want to read on and decide on the type you like best.

Daily-wear soft contac

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lenses. These lenses are made of soft, flexible plastic. The plastic allows oxygen to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ass through, which results in greater comfort for the wearer. Daily-wear soft lenses ne

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ed to be cleaned daily, using a special solution.

Daily-wear disposable soft lenses. T

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ese lenses are similar to daily-wear soft lenses with the exception that they are desig

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ed to be used and discarded within the span of one day. Usually, new lenses are worn ev

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ry morning and thrown away at night. Because you never keep a pair for more than a day,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you will never have to clean your disposable soft lenses.

Extended-wear soft lenses.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

xtended-wear soft lenses are lenses used for overnight wear and beyond. You can wear ex

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ended-wear soft lenses for up to a week without removing them.

Extended-wear disposabl

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

soft lenses. These lenses are designed to be worn continuously for up to a week, and t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hen discarded. Like other disposable lenses, they require little cleaning.

Planned rep

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

acement soft lenses. These are lenses that are replaced on a regular schedule, such as

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

very two weeks, monthly, etc. The big advantage of replacing your lens regularly is tha

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

it assures you of clean, bacteria-free lenses.

Rigid Gas Permeable (RGP) lenses. RGP

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

lenses are a new generation of contact lenses. These lenses have silicone in them, whic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

allows more oxygen to pass through, resulting in greater comfort and overall better ey

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

health. RGP lenses are also more durable and provide better vision than do soft lenses

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - The Varieties of Contact Lenses

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