E-Articles - Health and Fitness

Originally, contact lenses were very expensive, and were only available as permanent lenses. There were ma

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ny drawbacks to these lenses. Often, they were made of hard materials that were uncomfortable for the eye

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and were very heavy to wear. Also, they became a health hazard because of dirtiness. Even if the contact l

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ens is cleaned regularly, a buildup of various materials, including fatty lipids, dust, and other organic

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

material is inevitable.

As lenses decreased in price, the solution rapidly became obvious. Lenses came to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

be replaced more and more frequently, and the lenses became more and more comfortable to use. Nowadays, o

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ne can buy monthly, weekly, and daily disposable contact lenses. Lately, even colored and toric contacts h

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ave become available as 24 hour disposable lenses.

Contacts may be divided broadly into two categories, c

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

orrective and cosmetic. Most people that were contact lenses wear corrective lenses. These were the first

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

disposable lenses available. These lenses give you perfect eyesight, just as if your eye were perfect. Cos

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

etic lenses are designed with a different purpose. These lenses can change the color of your eye, or may a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

dd a design overtop of where your iris and pupil should be seen.

Corrective lenses are available for many

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

different manufacturers. The most popular brands are Acuvue and Ciba Vision. Acuvue Advance is probably t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

he most popular disposable corrective lens there is, while Ciba Vision is known as a more international br

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

and. Ironically, Ciba Vision is also known for its lens cleaner, Ciba Vision Clear Care.

Color Contacts,

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

on the other hand, are for people that want to spice up their eye color. Blue, pink, green, or brown eyes

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

are possible, no matter what your original eye color is. At halloween, make your disguise stand out by com

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

plementing it with contacts that give you animal eyes, or if you prefer, something not from this planet.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

In the end, it makes sense to go disposable. Each day, you can choose a contact to fit your mood, and you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

can be assured that the lens is clean and fresh. It really seems to be the low cost, no hassle alternative

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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