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The movie industry was quick to discover the potential that special effect con

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

tact lens could create in certain movie scenes.

We have all seen movie charac

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ers with inhuman looking eyes. Who could forget the trademark wild eyes of Da

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rth Maul in “Star Wars Episode I ?”

It was not only the color of his eyes, bu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the special blending effect that was used to incorporate the red outer ring w

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ith the yellow inner portion of the eye. It was a stunning effect that many h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ve desired to try out on their own eyes.

Animal Magnetism

Theatrical contact

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

lenses from Wild Eyes run the gamut with their line of special effect eyewear

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Maybe you fancy yourself a cat or a wolf, or maybe you just want to go ahe

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ad and get the bloodshot eyes before the party.

Whatever you are looking for,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

they will have it.

They even have a web page full of pictures sent in by sati

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

sfied customers. Lizard eyes, zebra eyes and the eye of the tiger can become

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

part of your costume or your haute couture.

The popularity of these speciall

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

y designed and colored lenses, especially around Halloween, has raised some co

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

cern about the safety of this lens.

The issue is not the lens itself, but the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tendency of some young people to share their special effects contacts. Many

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

f the popular young adult Halloween costumes are accented by the same wild eye

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

d look, so the lenses get passed from one party goer to another.

As is the ca

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e with any contact lens, these special effects contacts must be handled with c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

are. Proper hygienic practices should be used and contacts must not be shared

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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