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There is little doubt that one of the major possible causes of hair loss in women is stress. But the kind of stress that we are talk

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ing about here is not the common day to day kind of stress that we all experience. The kind of stress that can cause hair loss in women
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in
ong> is usually the result of some kind of sudden and extreme shock. Sudden and severe emotional trauma or severe physical trauma is usually needed in order t
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

o create the effect of sudden hair loss in women.

Some kinds of mental and emotional stress that can typically lead to hair loss in women can occur as a resu
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
t of the death of a family member or loved one; the ending a relationship through divorce or death; an extreme financial trauma such as a bankruptcy or losing
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro
a house. And this stress doesn't even need to be occurring to the person suffering the hair loss, but they could be occurring to someone that they love or ar
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
e very close to.

As far as physical stress and trauma that could cause hair loss in women is concerned, some examples could be severe and long-term illness,
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
urgical procedures and sudden and extreme physical trauma such as a car accident or heart attack.

The scientific name for this sudden hair loss i
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
n women is "telogen effluvium". In this specific hair loss condition hair follicles that a healthy and growing hair at the normal rate become ma
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ssively impeded, resulting in the severe slowing down of hair growth. The hair follicle then begins its resting phase, where hair growth is stopped altogether
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
In this phase the hair is relatively weak and falls out easily.

What can be confusing with this particular kind of hair loss in women
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a
ng> is that the results of the stress are not always immediate. Sometimes several months can pass after the traumatic event before any hair loss begins to occ
dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod
ur.

Oftentimes the woman who is experiencing their hair loss has forgotten the past dramatic event, and begins looking for answers to the sudden hair loss in
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
events that are happening in her life right now. Unfortunately the answers are not in what's happening now but in what happened several weeks or months befor
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
.

This in itself can create stress as there may be nothing occurring in a woman's life right now that could in any way lead to her losing her hair.

Irrespe
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
ctive of when the true cause of the hair loss occurred, once the hair loss cycle has begun the hair can fall out at an alarming rate leading to even more stre
ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust
ss for the woman who is losing hair, perpetuating the vicious cycle.

So in answer to the question can stress lead to hair loss in women, the answer is yes. B
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
t the stress needs to be something so far out of the ordinary that it can shock the body to the point that a woman's hair can fall out.

As with any kind of s
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
udden hair loss it is always best to seek the appropriate medical advice. A proper case history taking and diagnosis will often identify the cause of the woma
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
n's sudden hair loss, which in itself can relieve a significant amount of stress and any affect that stress may be having on the re-growth of the woman's hair

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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