E-Articles - Health and Fitness

Society these days is placing more emphasis on the way we look, and consequently people are increasingly concerned (s

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ome may say obsessed!) with their appearance. Hair loss in women, although not discussed as often as male hair loss

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is of great concern to many.

Eight primary factors in female hair loss are:

* Female pattern baldness. Many women

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

who suffer hair loss do so for the same reasons as men...androgenetic alopecia. This is a reaction to male hormones

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

in their bodies which basically converts testosterone into DHT in the same way as as in male pattern baldness. This

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

factor is usually of less concern to women than men due to the helpful influence of their own female hormones,

* Tel

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ogen effluvium This is a thinning of hair which can be the result of of stress caused by a dramatic event which shoc

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ks the hair growth cycle. Deaths in the family, disasters and even pregnancy are examples.

* Alopecia areata This

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

condition is characterized by patchy hair loss, both on the scalp or on other parts of the body. It is thought to be

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the result of immune system deficiencies, and in many cases, hair will regrow of its own accord.

* Child Birth-Preg

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nancy Hair loss in women can be the result of pregnancy and child birth. It appears that hair can go through a dorma

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nt phase often within 3 to 6 months after delivery.

* Diets Hair loss in women has also been attributed to intensiv

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e and often un natural diets that are common today.

* Illness or Infection These are problems also associated with

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hair loss in women and have been attributed to shedding or thinning of hair due to stress on the body. In many cases,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hair returns to normal when the illness is cured.

* Chemical Hair Treatments Bleaching and tinting are just two of

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

the harsh hair treatments that can cause adverse effects if used too often and should be stopped if the condition of

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hair deteriorates.

* Harsh Styling Constant pulling hair tightly in styles such as braids or even ponytails can al

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

so cause womens hair to fall out and should be avoided. Vigorous brushing and towelling of is another cause of thinni

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ng or damage.

If you are noticing hair loss and can not identify with any of these factors, a visit ot your doctor i

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s recommended. Home remedies may be an option, but stick with natural chemical free treatments if this is your choice

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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