E-Articles - Health and Fitness

If your mother suffered from excessive hair loss than it may well be that you will too. However, as the condition is rather r

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

arer in women than men it is always best to check with your doctor that there is not any other more serious cause such as dia

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

betes or hypothyroidism.

Many women experience a noticeable diffuse hair loss some months after having a child or after comi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ng off birth control pills. This is because the hormones involved will have caused more hairs than normal to go into the grow

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

th stage of the hair cycle at the same time while the pills were being taken or during pregnancy. This means that those same

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

airs reach the shedding stage of the cycle at the same time and because hormone levels have fallen there aren’t the same numb

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er to replace them all at once. This is a matter that normally rights itself after a few months and so isn’t really a problem

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

. A similar diffuse loss can be the result of stress. In that case it is obviously better to treat the stress than the scalp,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

which will gradually right itself. Such stress causes the hair to go into the resting stage, where it remains in the follicl

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e without growing, until it is pushed out by a new hair developing underneath it.

Finally there is hair thinning as part of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

he normal ageing process. As many as 13 % of women would say that they had some hair thinning before the menopause and by the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

age of 75 this percentage increase to about 75 %. It is due to the production of a chemical usually known as DHT, an excess

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of which in the body causes the hair follicles to produce thinner and thinner hair and finally to stop producing any at all.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Another important cause of hair loss in women is an autoimmune condition called tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

les/alopecia_areata_treatment.htm" target="_blank">alopecia areata in which the white blood cells attack hair follicles s

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

that hair production stops. After a while there may be regrowth, though it can be patchy and does not occur in every case. L

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

oss is usually on the top and at the sides of the head. Hair loss in women is not caused by washing your hair too often or b

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y brushing It too much. Dyes and perms will not cause permanent loss. Standing on your head will not make your hair grow more

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

thickly, nor will shaving your head. Nor is thinning hair a sign that you are any less than you were before Hang on to that

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

thought. But also get used to the idea that there is no one miracle cure for female balding whatever the advertisers may say

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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