E-Articles - Health and Fitness

Hair transplantation is on of the most common cosmetic surgery procedures performed today. The technology has dev

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eloped to the point where a procedure can be undetectable and quite good. In fact, I have personally performed th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ousands of transplant procedures with excellent results. Many of my patients have come back for second and even t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hird procedures and the results have been fantastic.

On the other hand, not everybody with hair loss will benefit

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

from having a surgical procedure for treating hair loss. For a number of reasons, you may not be a good candidat

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e and it would not be smart to undergo a transplant. In my experience, often times the most eager candidates are

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

actually the worst candidates. For instance, a young man in his late teens or early twenties may be noticing his

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

hair loss for the first time and is devastated. Due to the aggressive marketing for hair transplantation, he may

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

find himself lured into the procedure anticipating wonderful changes. Unfortunately, this may be the greatest pit

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

fall of hair transplant as the future hair loss is completely unpredictable. While the hair loss may run in the f

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

amily, one can never known which genetic factors influence the dynamic condition of the hair and scalp.

Another g

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

roup of people who may inappropriately be led down the primrose path is women who for some reason are experiencing

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rapid, temporary hair loss. Because each hair actually falls out after several years of growth, it is a very nor

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

mal process for everybody to lose hair. However, if the hair loss is somewhat synchronized, then temporary hair l

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

oss may occur and this “shock” loss may be very unnerving. Again, in this instance, a hair transplant may not be

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

indicated. In fact, a transplant may accelerate the temporary hair loss.

For these reasons and many more, it is

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

very important to have a complete hair and scalp analysis, examination and history. You may not be the best candi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

date for a transplant. Plus, if you are a good candidate, it may be better to either wait a while until your patt

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ern of loss may be more clearly defined or, it may also be prudent to condition your scalp for several months ahea

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d of time. That way, you will benefit the most from the transplant. After all, we all want happy hair, don’t we!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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It is so easy to sit down to complete an application and suddenly your mind blanks. You can't remember dates or names or telephone numbers. If you have a varied work history, you can't recall which job came first. If you have worked for the same employer for years, you forget when your duties changed or when you received a promotion.

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