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For a lot of people hair loss can be the result of a particular disease, genetic factor, hormonal influences and even chemotherapy treatment.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

However there is a category of hair loss that is arguably the most common and yet least talked about. Today there are a huge number of people taking pr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

scription medications that cause hair loss and in this article we will discuss three very commonly used classes of prescription medications that have

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hair loss as part of their side-effects profile.

Anti-inflammatory Medications: Use of anti-inflammatory medications (NSAIDs - non-steroidal-

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nti-inflammatory drugs) is incredibly common due to the fact that many people suffer from pain of one kind or another. Their use is increased due to the fact t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

at they are easily obtainable over the counter. Ibuprofen for example is one very popular drug in this category.

However they can contribute to hair loss in b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oth men and women and although much rarer children have been known to experience loss of hair due to the effects of anti-inflammatory medications.

If you need

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

to take prescribed anti-inflammatory medication, please check with your doctor about the possible side-effects in relation to possible hair loss particularly i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

you are being prescribed any of the following: Celebrex, Rofecobix, Lodine, Clinoril, Indocin, Voltaren Orudis and Naflon.

Anabolic Steroids:
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
g>Often associated with strength and power athletes such as bodybuilders and footballers anabolic steroids have a dramatic effect on the body's hormone system.
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
The reason why they are so favoured by strength and power athletes is the fact that they can increase muscle mass very quickly. However because of their effect
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a
on the hormonal system particularly in relation to male hormones such as testosterone, one of their side effects is hair loss in women and men.

Even a very sm
dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod
all amount of these medications can lead to sudden hair loss in anyone with any kind of sensitivity to DHT (a hormonal by-product of increased
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
levels of testosterone that is known to cause hair loss)

If you are taking or are considering taking any of the following be advised that hair loss may be one
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
of the undesired side-effects of doing so. Halotestin, Winstrol, Android, Danocrine, Depo-Testosterone, Metandren, Testred and Virilon.

Thyroid Medica
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
tions: Hair loss in men and women can be significantly increased due to the effects of certain thyroid medications. The two most common examples of th
ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust
roid medication that can lead to thinning of hair, loss of hair and even baldness are Carbimazole and Thiouracil.

When considering taking any prescription or
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ver-the-counter medication it is always wise to do the appropriate research and ask your doctor about the side-effects of these medications.

If you have a spe
.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
cific hair loss issue, the types of medication that you are taking could certainly be exacerbating if not causing the hair loss. By talking to your doctor, alt
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip
rnative options may be found, giving you the best treatment option for your specific health concern and minimizing the side-effects of the medications involved

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - Prescription Medications And Hair Loss - 3 Categories Of Medication That Can Lead To Hair Loss

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