E-Articles - Health and Fitness

Hair loss is a normal occurrence, our hairs is constantly going through a cycle which is growth->

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

resting-> shedding->growth...In some case the hairs that are lost are not replaced, this considere

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

as hair loss. Hair loss causes a decline in positive self-image and we start feeling inferior sim

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ply because our heads have lesser hair everyday. Some of you might think that hair loss only happe

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s to men, in fact, there are more and more of women lose their hairs as well.

There are some solu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tions when facing hair loss:

1) Shave your head (not for women of course). Many of men resort to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

have their heads and look great actually. It may fit their personality and style, and they feel co

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

mfortable that way. However, there are still some who do not want to get their lovely hairs shaven

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

off. For them, there are hairpieces or plugs, neither of which has been perfected to the point of

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

being undetectable, and both having a societal stigma as being somewhat tacky and undesirable.

2)

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Surgical treatments. Although it is extremely expensive, surgical treatment may be the best hair l

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oss solution as it is performed by qualified and experienced physician. There is surgical treatmen

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

designed to replace hair follicles to the scalp and grow new hairs where the old hairs had died.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

This treatment usually involves removing hair follicles from another part of our bodies and transp

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

anting it to the scalp. A very thin incision in the scalp is made and pulled back to create a new

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

home for the transplanted hair. Therefore, our new hairs are allowed to grow naturally in the new

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ocation.

3) Try some hair loss prevention products. It is less costly then surgical treatments. W

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

hile there is no such "magic pill" that can 100% promise men and women who take it will re-grow th

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ir hairs. Yet, there are some very promising and effective hair loss prevention products available

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

in market like Provillus, Procerin etc..

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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