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E-Articles - Female Pattern Baldness
Female pattern baldness can be termed as a major problem for women. This disease makes women have baldness in a bit similar pattern as men have in male pattern baldness.
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
It can start even in teenage.
What can be the causes of this female baldness?
There are various causal factors of female pattern baldness among women. The production of
What can be the causes of this female baldness?
There are various causal factors of female pattern baldness among women. The production of
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
androgenetic hormones and its effect on hair follicles can be termed as the main reason.
Role of androgen - The male hormone androgen plays key role in female pattern baldness,
Role of androgen - The male hormone androgen plays key role in female pattern baldness,
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
as they do in male pattern baldness.
Adrenal glands and ovaries are the main sources of androgens in females. Androgens like dehydroepiandrosterone (DHEA) produced by the adre
Adrenal glands and ovaries are the main sources of androgens in females. Androgens like dehydroepiandrosterone (DHEA) produced by the adre
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
al glands can be converted to testosterone by enzymes.
In females it is dehydroepiandrosterone (DHEA) from the adrenal glands that plays the key precursor of DHT. It needs conv
In females it is dehydroepiandrosterone (DHEA) from the adrenal glands that plays the key precursor of DHT. It needs conv
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ersion by both alpha 5 reductase enzymes and hydroxysteroid hydrogenase isomerase enzyme.
Genetic factor – Genes inherited from parents play a very important role in female
Genetic factor – Genes inherited from parents play a very important role in female
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
attern baldness. You may develop this problem if, suppose, your grandmother was suffering from it.
Alopecia Areata - Another cause of female baldness is Alopecia Areata. I
Alopecia Areata - Another cause of female baldness is Alopecia Areata. I
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
t causes a patchy hair loss from the scalp and sometimes eyebrows. And in this case the hair loss can be episodic and recurrent.
Traction alopecia - Traction alopecia also figu
Traction alopecia - Traction alopecia also figu
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
es among the list of causes. It entails consistent traction pressure on hair follicles. One possible cause of traction alopecia is tight braiding.
Trichotillomania - The compul
Trichotillomania - The compul
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
sive hair plucking called Trichotillomania also contributes to the cause of hair loss.
Telogen effluvium - Telogen effluvium also plays a causal factor in female baldness. It c
Telogen effluvium - Telogen effluvium also plays a causal factor in female baldness. It c
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
uses accelerated hair loss that may have hormonal, nutritional, drug-associated or stress-associated causes.
Post-pregnancy factor - The problem can also occur as post-pregnanc
Post-pregnancy factor - The problem can also occur as post-pregnanc
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
y development. It is sometimes found to happen after the discontinuation of birth-control pills. The condition is often accompanied by other signs of hormonal imbalance includin
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
excess facial and body hair.
Female pattern hair loss characteristics
In female pattern baldness, the hair of the affected woman starts thinning over the
Female pattern hair loss characteristics
In female pattern baldness, the hair of the affected woman starts thinning over the
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
top and front of the head. It is possible for any woman to face the problem. However, women generally suffer from this problem after their menopause.
On an average, women lose
On an average, women lose
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
around 100-125 hairs per day. It is a normal condition. The condition is apparently serious when the hair loss frequency is higher.
The pattern of hair loss may vary from perso
The pattern of hair loss may vary from perso
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
n to person. However, the hair loss patterns may include the following –
• Diffuse hair thinning over the entire scalp, often with more conspicuous thinning toward the back of
• Diffuse hair thinning over the entire scalp, often with more conspicuous thinning toward the back of
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
he scalp.
• Diffuse hair thinning over the entire scalp, with more conspicuous thinning toward the front of the scalp without involving the frontal hairline.
• Diffus
• Diffuse hair thinning over the entire scalp, with more conspicuous thinning toward the front of the scalp without involving the frontal hairline.
• Diffus
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
e hair thinning over the entire scalp, with more conspicuous thinning toward the front of the scalp, while involving and sometimes breaching the frontal hairline.
Women sufferi
Women sufferi
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
g from female pattern baldness tend to have miniaturizing hairs of varying diameters over all affected areas of the scalp. Hair miniaturizing is a feature of androgenetic alopec
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ia. However, the condition may also be related to other causes. For example, in post-menopausal stage a woman’s hair may experience miniaturization and become difficult to style
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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