E-Articles - Health and Fitness

Although we do not completely understand how hair loss and baldness is passed down through our genetics, what we do know is that some indivi

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

duals have hair follicles that are super sensitive to the “DHT” that runs through their blood.

DHT is a hormone with the initials standing

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

or “dihydrotestosterone”.

DHT is an androgen, created from testosterone, and is considered a male hormone. Surprisingly, even though this i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

a male hormone, women also have a small amount that runs through their blood, some higher than others. When a female inherits hair follicle

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s that are super sensitive to DHT, they will start to lose hair just as men do.

When a person inherits the genes for hair loss, their hair

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ollicles are also sensitive to DHT in other ways. Not only does a person's hair fall out, but they will have also inherited hair follicles t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

at, when regenerated through the three growth cycles, grow strands of hair that come back thinner and with less pigmentation.

This phenomen

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

on also clears up the mystery behind why some people have thinning hair that seems to change color as the person ages.

In other words, it i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

perfectly normal for everybody's hair to grow and then shed, and then regrow back again. This allows the hair to reenter the anagen phase,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hen the catagen phase, and finally the telogen phase, which results in a new strand of hair. But now, since a person's hair follicles are se

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sitive to the DHT in the blood supply, it prevents the hair from regenerating to its normal size after each repetitive growth cycle. They co

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

me back smaller and smaller. In time, a person's scalp will contain hair so small that it resembles fuzz, which can barely be seen, hence be

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

oming “bald”.

Don't Be Too Discouraged To Find Out You Are Loosing Your Hair

Although being genetically predisposed to hair follicles that

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

are sensitive to DHT may seem like a no-win situation, there is still hope! For starters, anybody who is experiencing hair loss can improve

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

their look by carefully styling their hair in a way that does not emphasize this loss of hair.

There are also many hair care products on th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

market that can help give the appearance of extra hair. And if you really wanted to make an improvement, there are many high-quality wigs a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d hairpieces that look as real as a natural head of hair.

Also, medications exist that are widely available that are designed to help prote

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ct sensitive hair follicles that are affected by DHT. Some medications can even help by reducing the amount of DHT in a person's bloodstream

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

which will help slow down the process of hair loss.

Although there is no “magic bullet” for everyone in terms of medication for hair loss,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

there have been some truly amazing results with treatment and medication where patients have experienced a total reversal of their hair loss

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Each year, thousands of Americans are placed in a troubling situation. That situation arises when their home floods. Flooding can occur due to hurricanes, thunderstorms with excess rain, or the break of a levee system.

Who will be the best market to target your products or services in 2006? If you thought USA or Europe, then you need to change your thinking.

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