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There are many different forms of alopecia hair loss (the term alopecia simply means hair loss) but baldness is the most common.

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

It can affect both men and women. Here are 7 facts you should know about baldness and other forms of alopecia hair loss:

1. Cau

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

es of baldness can include hereditary factors, various types of medications including chemotherapy, large doses of Vitamin A, and immune

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

system irregularities.

2. The following causes of alopecia hair loss can often be reversed:

birth control pills and p

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

egnancy

diabetes

lupus

low-protein diet

thyroid complications

menstruation resulting i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

low iron levels in the blood

hair pulling due either to anxiety or hair styles that demand tight braiding

chemical

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nd coloring treatments for the hair as well as excessive shampooing

3. Anyone coping with hair loss should take simp

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e precautions such as avoiding the use of blow dryers or combing the hair while it is wet and especially fragile.

4. Chemotherap

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

drugs can affect the cells in the hair follicle responsible for hair growth. In such cases the hair often regrows after the treatment i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

finished although it may have a different texture and color.

5. If you are affected by alopecia hair loss, you can learn to cop

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

by:

Educating yourself as much as possible about the condition through personal research and obtaining information from medi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

al professionals

Joining support groups where you can discuss your condition and the implications in your life. The internet o

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

fers forums and discussion groups you may wish to join.

Adjusting mental attitude about self-image, avoiding over-concern abou

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

appearance, and using camouflage, wigs, or cosmetic options to minimize the overall visual effect of hair loss.

6.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

inimize discomfort from alopecia hair loss by using sunscreens on the scalp and face or by wearing wigs, hats or scarves to protect the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ead.

7. In the case of alopecia hair loss due to the immune system turning on the hair follicles by mistake, corticosteroid drug

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

may be administered to suppress the immune system. Corticosteroid drugs can be given through injection, orally, or in topical creams or

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ointments.

Alopecia hair loss can be distressing there is no doubt. However, a thorough education about the subject and proper diagnosi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

from a qualified medical practitioner can do much to alleviate undue anxiety.

Here are some organizations you may wish to keep

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n mind as you learn more about alopecia hair loss:

National Alopecia Areata Foundation: naaf.org

American Hair Loss Council: ahlc.or

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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