E-Articles - Health and Fitness

A balanced diet is necessary for supplying adequate amounts of nutrients, minerals and vitamins to the body .l

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ack of a proper diet often results in hair loss. Hence, hair loss can be treated by intake of dietary suppleme

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ts, like minerals and vitamins, especially the B Vitamins (B5, B6, and niacin), Biotin, Inositol and Folic Aci

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

d. It has been proved that ample intake of vitamins counters hair loss and promotes the growth of healthy and

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hiny hair.

Vitamins can help in treating hair loss in a number of ways:

- Vitamins obstruct the production o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

f di-hydro testosterone or DHT – one of the principal causes that trigger hair loss.

- Vitamins revitalize da

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

aged hair follicles and thereby promote hair growth.

- Vitamins nourish and heal the scalp.

A number of vita

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

min formulas have topical application, like shampoos or serums that are to be applied on the scalp. This provi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e a two-pronged approach to combating hair loss – both from inside the system and from outside the body. Howev

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

er, it should be borne in mind that there is no “quick-fix” method for curing hair loss troubles; all the prod

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

cts require sustained use for optimum results.

B-Vitamins

Food items like beans, peas, cauliflower, s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oy beans, and eggs are sources of vitamin B, which is very important for the health of the scalp and hair. Vit

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

mins B3 (niacin), B5 (also called pantothenic acid), and B6 (pyridoxine) should be taken as nutritional supple

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ment for treating hair loss. Folic acid is a type of B vitamin (B9) that delays the onset of grey hair, and is

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

useful in preventing hair loss.

Biotin

Biotin is essential for healthy hair and skin and may be effec

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tive in preventing male pattern baldness. Brown rice, brewer’s yeast, sunflower seeds, green peas, soybeans, o

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ts, lentils and walnuts are excellent sources of this vitamin. Supplements can also be used to counter excessi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ve hair loss.

Other Vitamins:

Inositol is for healthful for hair.

Vitamin C helps in increasing the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

blood circulation in the scalp and ensuring that the hair follicles get adequate supply of nutrients.

Vita

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

min E

This vitamin aids in improving uptake of oxygen, which leads to better health of the scalp and hair

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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