E-Articles - Health and Fitness

Omega 3, DHA and Great Taste

Fish is the health food of the century and baby boomers are buying it up by the pound. The leading reason for fish being a health hero is fish

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is practically the only natural source of Omega 3 fatty acids. Omega 3 fatty acids are an essential nutrient that almost all Americans fall short on. In this low-fat, no-fat

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

world this may seem strange. Simply put, the human diet requires a balance of certain fats.

Grill it, poach it, broil it, bake it. Any way you cook it, fish really is brain

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

food. Not only that, but according to research, also food for your heart, prostate and more. Fish, particularly fatty fish, is an excellent source of the Omega-3 fatty acid

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Omega-3 has been shown to be beneficial to our health in a myriad of ways. The American Heart Association recom

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ends two servings per week of fish such as salmon, char, mackerel and herring because they contain more Omega-3 than lighter fish such as cod or halibut.

Fish is lower in s

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

turated fat, total fat and calories than comparable portions of meat or poultry, the experts note in the February issue of the Mayo Clinic Women's Health Source.

New Englan

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Journal of Medicine in 1997 reported reduced cardiovascular disease in people consuming fish high in omega-3 polyunsaturated fatty acid (PUFA). It is a well known fact that

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

PUFA is helpful in reducing cholesterol level. People consuming PUFA are less likely to suffer from cardiovascular disease. As humans are not able to synthesize omega 3 poly

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nsaturated fatty acid (PUFA), they must be supplied to the body in the diet. These fatty acids accomplish the synthesis of other essential fats.

French researcher Pascale B

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

rberger-Gateau found that just one serving a week of fish decreased the risk of developing dementia by 30 percent. Eating fatty fish several times a week may also lower the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

risk of developing prostate cancer by as much as half.

A Swedish study of 3,500 postmenopausal women eating two servings of fatty fish a week found they were 40 percent les

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

likely to develop endometrial cancer than those eating less than one-fourth of a serving a week.

According to Science Journal [278: 1904 - 1905 (1997)], 7 ounces of fish p

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r week is considered to be good and healthy for a woman of 60kg.

Fish consumption during pregnancy may result in a lower risk of preterm delivery or low birth weight. DHA i

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

particular is essential for infant brain and eye development. It may even help prevent postpartum depression.

However, be aware that several types of fish - swordfish, sha

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

k, king mackerel, tuna and tilefish can be unsafe in any amount for pregnant or breastfeeding women, women of childbearing age who may become pregnant, and small children, a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

cording to the U.S. Food and Drug Administration's advisory. There is concern that these fish may contain high amounts of methylmercury, which has the potential to cause ner

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ous system damage to a developing fetus and other damage to those at risk. Methylmercury is an industrial contaminant that sometimes finds its way into the waters in which f

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

sh live.

Overall, fish is an important part of a balanced diet; it is full of vitamins, and other nutrients, including essential fatty acids. It helps in lowering cholester

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

l level and in controlling blood pressure. It is therefore important that you do not cut fish from your menu but be little cautious about the source and the amount of intake

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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