E-Articles - Health and Fitness

You’re eating lots of fruits and vegetables every day, but are you sure you’re getting the most nutritional

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

value from them, and what can you do to improve how many nutrients you are getting. To understand we need

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

o take a deeper look at the trip that fruits and vegetables make to get to your table.

Many different fact

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ors can affect the nutritional value of fruits and vegetables before they reach your table. The two most im

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ortant are time and traveling conditions. The shorter the time frame that the fruit is packed until it reac

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hes your table the better. If you are lucky enough to have a home garden try to pick your vegetables early

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

n the morning for peak flavor and nutritional value. The next best choice is to use a local market stand. G

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

enerally the foods they are selling were picked within a few hours of being set out for sale. If there are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

o local markets in your area like most people you’ll be forced to shop at a supermarket.

Before any produc

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e reaches your local supermarket it must first be picked, and packaged. If the food is coming to you from t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e same state or neighboring state chances are it was picked within 48 hours of reaching the stores shelves.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

If you’re produce is making it way from California to New York chances are it was picked 7 to 10 days ago.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Why do you need to be concerned about when something was harvested? When any produce is picked off of the v

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ine it is at its nutritional peak value. It starts to lose that value as time passes, the more time that pa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ses, and the more value it loses.

The second biggest contributor is handling. If care is taken no to bruis

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e or damage the exterior skin produce will last longer. Additionally storing a produce at the proper temper

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ture will also help slow down the loss of nutrients. Here’s where it gets a little tricky, some fruits like

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

temperatures as high as 60 degrees, and other prefer temperatures in the mid 30’s. So the longer your food

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

is in transit, and the more care that it shown to handling it properly the more packed with nutrients it is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - Getting the Most Nutritional Value from Fruits and Vegetables

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