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  • E-Articles - What You Should Know About Obesity As A Deadly Disease

    Did you know that obesity is now classified as a disease and that physicians are compelled by medical ethics to offer treatment for all diseases? Weight control experts believe
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    that obesity carries medical risks so severe that for a physician to delay offering treatment would be a form of malpractice. What does your doctor say about your weight?

    Not o
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ly will you reverse a multitude of disease risks if you lose weight, you will acquire a new sense of self-esteem and improved quality of life. Certainly, to be able to find and
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    utilize the opportunity to achieve weight loss and the attendant benefits is your desire.

    Obesity and Diseases

    Excessive body fat is associated with increased risks of
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    isease. For example, even a modest weight gain during adulthood brings an increased risk of diabetes among women. Excess weight has been named as the cause of up to half of all
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ases of hypertension, and thus increases the risk of stroke.

    Often weight loss alone can normalize the blood pressure of an over weight person; some people who suffer from hype
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    rtension can tell you exactly at what weight their blood pressure begins to rise. Being over weight also triples a person's risk of developing diabetes and all of its associat
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    d ills. If hypertension or diabetes runs in your family you urgently need to attend to controlling body over weight.

    The unhealthy risks of over weight are so many that it has
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    been declared a disease. Obesity, in addition to diabetes and hypertension predispose other health risks such as high blood lipids, Cardiovascular disease, sleep apnea (abnormal
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    pauses in breathing during slept)

    Other serious health conditions associated with Obesity are: Osteoarthritis, abdominal hernias, cancer, varicose veins, gout, gallbladder dise
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    se, arthritis, respiratory problems (including pickwickian syndrome, a breathing blockage linked with sudden death) liver malfunction, complications in pregnancy and surgery, fl
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    at feet, and even a high accident rate.

    Moreover, after the effects of diagnosed disease are taken into account, the risk of death from other causes remains almost twice as hig
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    for people with lifelong obesity as for others.

    Rate of weight loss

    Successful long term weight control requires controlled low loss of body fat without cyclic “on-aga
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    in off-again” dieting. Losing a pound a week helps maintain muscle while preferentially losing fat tissues.

    Commit to exercising for life

    Exercising for life helps keep
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    the body engine revved up, so that more calories are burned by muscle and less insulin is required to dispose of elevated blood sugar following meals. Even a daily half-hour of
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    igorous walking will help maintain weight.

    Commit to changing eating habit.

    Your diet is the basis of your health. Eating right or wrong makes you either over weigh
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    t or drives your over weight to obesity levels. Let your nutritionist or doctor guide you, so that you consume only the necessary calories and at the required intervals

    BODY
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    MASS INDEX

    (BMI) is a standard for body weight based upon the measurements of height and weight. This is one of the most useful relationships; it can be used to asses healt
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    h risks associated with overweight and it can be used as a therapeutic guide. There is a high degree of correlation between BMI and body fast. BMI is based upon surveys of lean
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    dult between the age of 20 and 29 to calculate the index of fatness.

    BMI = Weight(kg)/height(m)2

    Take care of your weight before it becomes a source of serious health problems


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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