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E-Articles - Obesity Is a Growing Problem
The number of overweight children ages 6 to 11 doubled in the
last 20 years; in that same period, the number of overweight
teenagers tripled. Between 1960 and the present the number of
Americans 20
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
and over who are overweight grew from 45 percent to
66 percent. The number of Americans 20 and over who are obese
grew from 13 percent to 31 percent!
How did this tremendous increase in body fat come
How did this tremendous increase in body fat come
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
about? Two
major reports were released in the late 1980s which identified
saturated fat as the culprit responsible for high cholesterol and
clogged arteries. One of those reports was the 1988 Surgeo
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
General’s Report on Nutrition in Health. The public was informed
that they should reduce their consumption of fat.
It was in the 1990s that food companies provided consumers with ‘low fat’ and ‘li
It was in the 1990s that food companies provided consumers with ‘low fat’ and ‘li
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
ht’ (or ‘lite’) products. Remember the ‘lite’
beer commercials? To produce these low fat products, food
companies substituted vegetable fats and sugars for animal fats.
But calorie-wise, there was o
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
nly a minor difference.
Consumers, however, were not educated to consider total calories. As far as they were concerned, ‘low fat’ meant that the food product was better for their health than the reg
Consumers, however, were not educated to consider total calories. As far as they were concerned, ‘low fat’ meant that the food product was better for their health than the reg
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
lar version.
Almost all consumers, including myself, thought that way. In the
90s the average American did not know that there were good fats
and bad fats and good carbohydrates and bad carbohydrate
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
.
The United States Department of Agriculture (USDA) released its dietary guide called the food pyramid to the American public in 1992. The base of the pyramid from which the majority of the food s
The United States Department of Agriculture (USDA) released its dietary guide called the food pyramid to the American public in 1992. The base of the pyramid from which the majority of the food s
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
ould come from consisted of cereal, breads, rice and pasta (5
to 11 servings.) Unfortunately no distinction was made between
refined or simple carbohydrates such as white bread and rice and
complex
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
carbohydrates such as sweet potatoes and brown rice.
That same pyramid had meat, poultry, fish, dry beans, eggs and nuts (2 to 3 servings) one level down from the top. At the very top to be eaten spa
That same pyramid had meat, poultry, fish, dry beans, eggs and nuts (2 to 3 servings) one level down from the top. At the very top to be eaten spa
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
ingly were fats and oils. The American public
wasn’t told that nuts contain good fats and cold-water fish such
as mackerel, salmon, and herring contain omega-3 fatty acids
which are extremely benefi
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ial.
So, based on misinformation from the USDA, and low fat products from food producers, the average citizen increased his caloric intake by eating low fat, highly processed carbohydrate laden coo
So, based on misinformation from the USDA, and low fat products from food producers, the average citizen increased his caloric intake by eating low fat, highly processed carbohydrate laden coo
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ies, crackers and potato chips. He also decreased milk
consumption and increased his consumption of diet and regular
soda (liquid candy.)
The medical establishment discovered something very strange.
The medical establishment discovered something very strange.
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
More
and more people, including children, were getting bigger and
bigger. And as their waists increased on the standard American
diet (SAD), the incidence of chronic diseases such as heart
disease
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
type 2 diabetes and strokes kept pace.
Advances in nutritional science and healthy living has corrected to a large extent the USDA’s 1992 food pyramid. The revised 2005 version distinguishes between
Advances in nutritional science and healthy living has corrected to a large extent the USDA’s 1992 food pyramid. The revised 2005 version distinguishes between
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
good and bad fats and good and bad
carbohydrates. It also includes exercise as an integral part of a
healthy lifestyle.
A study was released recently which noted that Americans are not eating enoug
A study was released recently which noted that Americans are not eating enoug
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
fruit and vegetables. Fruit juices and drinks and
canned fruit in syrup don’t count. Refined carbohydrates such as
white rice and bread, french fries and of course sodas (regular
and diet) still ru
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
le among the public. Until these unhealthy food
choices are drastically reduced, or even eliminated, Americans
will continue growing. This growth will increase the risk factors
for chronic degenerat
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
ve diseases (think cancer, heart disease,
etc.) even more and result in even higher healthcare expenditures
and costs.
The Robert Wood Johnson Foundation estimates that total costs to fight obesity
The Robert Wood Johnson Foundation estimates that total costs to fight obesity
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
in America is an estimated $117 billion dollars. This
figure includes lost productivity and direct health care costs. The
foundation says that $14 billion alone is spent on battling
childhood obesity
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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