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  • E-Articles - Childhood Obesity Epidemic

    We are all aware that obesity is a major problem in our society. Yet usually, in thinking about the problem, we only focus on the adult probl
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    em. But the fact is, obesity among children has doubled in the last two decades. That’s right. Not only are more children becoming obese, the
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    are contracting the diseases that are typically associated with obesity. These include high blood pressure, asthma, high cholesterol, type 2
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    diabetes, irregular menstruation, low self esteem, sleeping problems, as well as hip and knee problems.

    The key to preventing obesity is to
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    teach children healthy patterns of living at an early age. Obese children have a high percentage of becoming obese adults; if one is obese as
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    a teenager, then those chances are even greater. And children who have obese parents are also a lot more likely to encounter the problem the
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    selves, whether in adolescence or in adulthood.

    It is not the parent who should determine whether their child is overweight or not, but a ph
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ysician. This is because young children tend to grow in spurts, which might have an effect on the individual child’s body structure and growt
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    pattern. A qualified doctor should be able to assess the child’s proper body mass by evaluating his or her weight and height in relation to
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    the child’s previous history of growth.

    Parents should keep in mind that weight loss is not a healthy or proper method for young children to
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    employ, as their bodies are still developing. Unless a doctor assigns your child to be put on a diet for specific medical reasons, dieting sh
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    uld not be encouraged in young children, as it could deprive them of the nutrients and energy they need to grow.

    Rather, the aim should be f
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    or the child to maintain their current weight while waiting to grow in to their normal height. By reducing fat and increasing physical activi
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    y, the vast majority of overweight children will eventually grow in to their normal weight.

    The key to combating obesity seems to lie in ene
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    rgy balance – that is controlling the amount of calories that are consumed versus the amount of calories that are expended. So in other words
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    when we talk about fighting obesity, we have to talk about both eating and physical activity. This might seem pretty simple, but the fact is
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    eating and physical activity are caught up in a number of complex social and environmental forces.

    In the last three decades that have seen
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    the epidemic of obesity balloon out of proportion, the society has undergone major changes. Children now spend more time on activities such a
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    s watching television and playing video games rather than playing sports or exercising. What’s more, in a society that is increasingly “on th
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    go,” children rarely eat at home now with their parents, and when they do, fast food is often the solution for those who are time challenged


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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