E-Articles - Health and Fitness

Look around and you can’t help but notice the problem – 1 out of every 3 Americans is carrying around extra weight. Weight that puts them at risk for diabetes, heart diseas

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e, cancer, hypertension, shortened life span, stroke, and high cholesterol just to name a few. Okay, so you know there is a problem now how do you solve it or better yet wh

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

re do you begin? The first step any individual with a weight problem should see their physician for a full evaluation and discussion regarding safe weight loss goals and pl

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

an of action.

There will be many items that your physician will discuss with you including your current medical problems and what impact they will have on your goal of weig

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t loss. You will learn what your body mass index is which is your weight in kilograms divided by your height in meters squared. This gives a rough estimate of obesity seve

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rity. The higher the number the higher your risk for health problems down the road. A BMI between 25-30 is considered overweight and beyond 30 is obese. Your doctor will

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

lso discuss safe weight loss goals. You should not lose more than 2-3 pounds per week or 8-10 pounds per month. Keep in mind the long-term goal of keeping the weight off.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

You will notice that men tend to lose weight more quickly than women because they have more muscle mass which burns fat more quickly.

Now to the difficult part, what “diet

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

do you use? There is no simple answer here except to remember your weight is like a bank account the more you put in (food) the more interest (fat) you are going to genera

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

te. Your goal should be use more than you are consuming. There are literally thousands of diets to follow but I would suggest sticking to the basics. The less processed t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e food the better it is for you. Green beans are good for you but less so when they come from a can with all the additives. Stick to the whole foods (raw fruits and vegeta

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

les), avoid fried meats (especially red meat), and keep sweets to the bare minimum. Remember all things in moderation will increase your likelihood of success. You may wan

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t to do some research on what is considered your target calorie intake for your gender, height and current weight. Your physician should be able to help you find these reso

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rces.

You must understand that it will be very difficult to lose weight with dieting alone. Any good weight loss program will incorporate a good diet and an exercise progr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

am appropriate for your current health status. I almost always recommend that my patients begin with a walking program. I don’t care if it is only 5 minutes a day to start

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

as long as they start. The human body has an amazing ability to adapt quickly and this will be evident as walking becomes easier with time. The pace should be fast enough

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

that you are a bit breathless while in a conversation. You should need to stop and take a breath after a sentence or two. Two more very important components to an exercis

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

program is stretching and resistance training. Stretching should be done after a warm-up and during the cool-down phase. Resistance training should be done 2-3 times per

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

week with a 24 hour resting period between workouts for each muscle group.

There are also weight loss medications and surgery, which should be considered a last resort afte

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

all conservative measures have failed. Again these are all only suggestions and you should consult with your physician before beginning any weight loss or exercise program

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/261558/e-article-Obesity-Serial-Killer-of-the-21st-Century.html">Obesity: Serial Killer of the 21st Century</a>

BB link (for phorums):
[url=http://www.e-article.org.ua/article/261558/e-article-Obesity-Serial-Killer-of-the-21st-Century.html]Obesity: Serial Killer of the 21st Century[/url]

Writing a resume is hard work. You must write your resume correctly; it must be perfect! Any blunders in your resume could cost you the job.

True friends do not hesitate giving their lives for their friend's benefit. We have heard stories of great friendships since childhood. What about you? Do you think you are a good friend?

With a contact lens prescription in hand, it's possible to buy your contact lenses from stores, the Internet, over the phone, or by mail. In the U.S. contact lens marketplace, 82 percent wear soft lenses, 16 percent wear rigid gas-permeable and only 2 percent wear hard. Contact lens sales are regulated by the FDA (Food And Drug Administration) and the FTC (Federal Trade Commission.)

Tags

Links

E-Articles - Obesity: Serial Killer of the 21st Century

Related Articles: