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Sometimes it seems too easy - go and have a tummy tuck, and instantly all your weight problems will be solved. Well, it's not that easy. A tummy t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

uck, also known as abdominoplasty, is a major surgical procedure, with all the usual risks involved. Yes, the purpose of a tummy tuck is to removal

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

excess fat and skin from the lower area of the abdomen, but you need to realize that you will be left with a permanent scar, and it may take well ov

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r six months for you to recover from the surgery. Still, thousands of tummy tucks are performed successfully every year.

The first step is to spen

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

d some time with your surgeon, so that you can ask all the questions you need to about the procedure, and discuss any issues that relate specificall

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to your own condition. Your surgeon will also detail all the required pre-op and post-op procedures, so that you are fully prepared for the operat

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

on.

It usually takes a few hours to perform a tummy tuck, and a general anesthetic is used in most cases. Sometimes the surgeon may use a localize

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d anesthetic and sedatives, but this can be uncomfortable for the patient, despite the fact that they don't feel any pain.

The first step in abdomi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

oplasty is to make an incision across the whole of the lower abdomen. This usually runs hip-to-hip, right above the pubic bone. Sometimes only a p

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rtial abdominoplasty is performed, which only requires a much smaller incision. Next, the navel is removed from the surrounding tissue. This allow

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the surgeon to reconstruct the abdominal area in a natural looking manner. The surgeon then reveals the abdominal muscles and pulls them together

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to tighten them, and stitches them into place. This tightening of the abdominal muscles is what's meant by a tummy tuck, not the removal of fat. T

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e skin is then stretched back over the abdomen, any excess being removed, and then the navel is repositioned. Once everything is in place, it's all

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

stitched together and dressings are applied.

Normally the patient remains in hospital for several days, so that the incisions can start to heal and

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

it can be confirmed that there are no major complications. Some patients are released on the same day, but this is unusual. You will need to avoi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

activities such as heavy exercising and driving until your recovery is complete, and your surgeon will provide you with that sort of information as

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

part of your post-operative care.

It's common to feel discomfort and pain in the abdominal area after surgery, and pain medication is usually requi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

red to keep this under control. The total healing process, however, takes many months, and it's very important that you don't resume any physical a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tivity before you are ready. Certainly the tummy tuck procedure produces effective, permanent results. So if you don’t mind the scarring, it can b

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

a great way to feel and look better. If you develop a regular exercise program and sensible eating habits, the beneficial effects can be permanent

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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