E-Articles - Health and Fitness

Obesity is a health condition wherein body fat is increased and unused, reaching a dangerous point in a person’s health. This hap

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

pens when the energy from food intake is greater than its use. This causes the body to store energy as fat.

There are a number o

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

factors that cause obesity. Some of which include a genetic predisposition, an underlying illness, eating disorders, medications

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, poor mental health, lack of sleep, etc. Obesity causes quite a lot of damage considering the number of related diseases that ar

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

brought on by this health condition. To make matters worse, obesity incidences has increased that it is now considered a global

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hreat. The rates of child obesity incidences have, in fact, tripled in the United States since 1997. As a response, we’ve tried t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

o combat obesity with diets, exercise, behavior modification, surgery and more recently, drug therapy.

However, nothing beats pr

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

vention by a long shot. Its like building a good defense system. The goal is to prevent obesity, specifically child obesity from

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eaching into adulthood. If you’re your child is showing symptoms of child obesity have your child diagnosed as early as possible.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Early detection of the symptoms of child obesity will yield better results because the longer bad habits are allowed, the harder

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

it is to remove them.

Understand that the symptoms of child obesity may include asthma, type 2 diabetes, heart problems, increas

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d blood pressure, increased cholesterol level, sleep apnea, bone and joint problems and psychological problems. Factors that cont

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ribute to the symptoms of child obesity are excessive television watching, minimum to no exercise and excessive eating especially

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of high-calorie and high-fat foods. Obesity cannot be diagnosed through one test. If your child is up for diagnosis, the child’s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Body Mass Index shall me measured, as well as his waist circumference, forms or fat and other assessments. A child can be conside

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

red ‘medically obese’ when the child’s weight have posed health risks such as those stated before. You can determine the degree

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

o which the child’s obesity has reached by calculating the child’s Body Mass Index (BMI). Just multiply the child’s weight in kil

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

grams by the square of his height in meters as shown: BMI=kg/m2. The resulting number should be compared to the appropriate age p

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ercentile.

Remember that an overweight child can be at risk of becoming obese. If the symptoms of child obesity are quite obviou

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

, take action and muster both yours and your child’s courage to fight the condition before it worsens. Life is much too important

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - Is Your Child Showing Symptoms of Obesity?

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