E-Articles - Health and Fitness

Being overweight or obese may pose health-related risks. Overweight and obesity have been considered as the leading cause of stroke

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

and hypertension, cancer, and type 2 diabetes milletus. Insulin resistance can result to diabetes. Obesity and insulin resistance ar

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

two of the most leading causes of morbidity in developed and developing countries. The number of people that are obese is growing a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

well as the number of people suffering from insulin resistance.

But what is obesity and what is insulin resistance. How do obesity

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

and insulin resistance affect our health and how should they be prevented?

Obesity occurs when the body mass index (BMI) goes way b

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

yond the normal. A BMI that is beyond 25 is considered overweight while 30 is already at the obese level. Obese people have a tenden

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

cy to develop insulin resistance, which may then turn to become diabetes if prolonged. The pancreas produces hormone called insulin.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

The body uses insulin in utilizing blood glucose. Insulin resistance happens when the body no longer absorbs the insulin that the pa

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

creas produces. If this happens the person will soon acquire type 2 diabetes that could be debilitating.

More people are now suffer

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ng from these two diseases. They should now be extra careful because it could result to health complications. Obesity and insulin r

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sistance should be managed if not avoided. Sedentary lifestyle and too much intake of food rich in carbohydrates can cause obesity t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

hat might well lead to insulin resistance. So, at any rate it must be avoided.

Physical activity is the key to alleviating their po

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

sible harmful effects. Regular exercise is the safest and the cheapest remedy. If obesity is addressed, chances are insulin resistan

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e is minimized, so it is like hitting two birds with one stone. This regimen is always a win-win strategy to achieving that good hea

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

th again. Jogging around or any physical exercise and eating the right kind of food that are less in fat, sugar and salt will surely

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

pay off in the long run. A great deal of self-discipline among people suffering from these diseases is vital. No amount of remedy ca

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

n ever help anyone if disease management is not strictly followed.

The financial burden of these two diseases could be depressing.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

f not addressed immediately they could eat someone’s saving to the core. The cost of medication is very expensive. It could be psych

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

logically and physically draining as well.

A good life can be enjoyed to the full if we are disease free. Prevention is still the k

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y to that good life. So be always informed and keep yourself healthy. Stay away from obesity and insulin resistance health problems

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - Obesity and Insulin Resistance

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