E-Articles - Health and Fitness

The incidence of child obesity is rising fiercely. There are approximately 30.3% of American children ages 6 to 11 years is overwe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ight. While 15.3 % is already obese. It is also apparent that a child with at least one overweight or obese parent is likely to be

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ome the same.

Should you map the source of child obesity, it would originate from home and the immediate environment. Children p

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ck up habits and inherit traits from those around them. Some kids grow obese due to a genetic predisposition inherited from one or

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

both parents. Some grow obese due to an entirely different cause: the couch potato lifestyle. Adding to the mayhem of the inciden

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e of obesity is the reduction of physical activity. Because kids nowadays have technology as entertainment and hopefully a source

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

f learning, they become subject to less physical exertion whether they intend to or not. Back then kids played out in the sun runn

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ing climbing trees. Now they destroy armies of zombies or accomplish missions assigned by a CIA handler or hack other computers. A

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

though parents do not intend for their kids to sit all day watching the television or playing a computer game until their eyes pop

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

out, parents sometimes have no control being unable to be with their child 24/7. The prevalence of this lifestyle has a generation

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

factor wherein kids grow addicted to such hobbies while trying to keep up with their peers. The incidence of child obesity is also

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

brought by the most obvious causes: the fast-food, high-calorie and high-fat diet that the west is so fond of. Perhaps if kids we

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e born into a fad for vegetables and fruits, obesity would not have been a growing health threat to the world. At this point, the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ncidence of child obesity has raised so due to the change in lifestyle brought about by technology and food sources. Notice that t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

he incidence of child obesity is worse in developed countries where food is abundant and technology is within a child’s grasp. How

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ver, the incidence of child obesity among developing countries is likely to follow suit if prevention of the same events is not un

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ertaken.

Among the causes of obesity, there are the unfortunate underlying factors contributed by genetic disorders, illnesses, m

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

edications, specific diets due to certain illnesses. These cases vary among subjects whose obesity condition may or may not depend

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

on the immediate environment but solely according to an existing medical condition.

Kids are also subject to unhealthy mental con

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

itions and eating disorders. The two are packaged together that there is no definitive answer as to whether which caused the other

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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