E-Articles - Health and Fitness

“Obesogenic adj. related to or contributing to obesity”

Our increasingly "obesegenic environment" makes it "easy to eat crap and not exercise,"

"Genetics loads the gun, and the environment pulls the trigger." AHH! Isn’t it lovely we h

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ave a new word to describe our ever expanding girth; this is nothing to celebrate about my friends.

The causes for obesity are fairly self explanatory, too much food in vs. too little going out in the form of physical exertion equals ob

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

esity.

So what’s changed over the previous 20-30 years? Well, for starters we have an abundance of labor saving devices such as microwaves, toasters, computers, car washes, refrigerators defrost themselves, we get a ride to school, and

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

we don’t even need to drag ourselves up from the sofa to change the television station for goodness sakes! Combine that with current trends in North America to eat a diet of over half the calorie content coming from fat and sugar, and ba

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ng very shortly we’ll all explode!

The term “obesogenic environment” popped up in the 1990s to describe an environment that encourages the over indulgence of energy dense foods, that is, foods high in fat and sugar. Eating fat has very

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

little effect on suppressing appetite, nor has sweet foods for that matter. And guess what? Fast foods and processed foods are full of fat and sweeteners. How else do you think you could chow down a Big Mac or two, large fries, large sof

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t drink and still have room for a desert? For most of the population, an average fast food meal uses up, 100% OR MORE of their daily calorie requirement. It is little wonder we are fat and getting fatter.

Ok let’s talk about genetics fo

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a moment, genetics play a role, but the gene pool in North America has not changed all that much in the few decades during which obesity has become so dominant. Genetics must be combined with an environment conducive to gaining weight,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

an environment that has been termed "obesogenic", in order for the explosive increase in both childhood and adult overweight and obesity to have occurred. Saying that may I tell you to cancel out “I got the fat gene” I was meant to be fa

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t excuse, HMM! Got your attention didn’t I?

If the obesity epidemic in North America is not controlled by YOU THE INDIVIDUAL and YOU do not take responsibility for YOUR CHOICES, almost every North American will be obese within just a fe

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

w more generations. I am sad to say this but "becoming obese is a normal response to the North American environment" do we as a society really want to be labeled as “fat is normal” HMM!

This hits my nerve in a way that makes me GRRR at

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

the “National Association to Advance Fat Acceptance” and our governments relax people by no means am I trying to offend you all I am saying is STOP and think of what environment you’re creating for yourself. We don’t need bigger caskets,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

bigger chairs, bigger beds or weight loss pills WHAT WE DO NEED is to get ourselves properly educated on nutrition and fitness not on how to stay fat or get fatter that’s not in my books, I am against all fat acceptance organizations we

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

simply do not need them I rather see that money be spent on more specialized obesity programs for adults/children, more so I would like to see manufactures stop making bigger then life products we don’t need them its time for a reality

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

heck if you cant fit into a MRI too bad for you your health care will suffer, if you cant fit into a roller coaster with your child that’s very sad, if you don’t fit in a normal sized bed sleep on the floor, if you cant play with kids ou

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tside because its hard to move stay inside watching them have FUN FUN FUN from the window, get the picture? Good lets get to the good stuff shall we?

Let’s improve our environment.

Few things we need to do when we are embarking on a he

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

althier lifestyle and it all starts in the kitchen:

- Remove all junk food and soft drinks out of the house; this includes every room in the house not just the kitchen.

- Don’t turn on the TV you don’t need it its making you and your f

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

amily fat!

- Remove all video games; get them out of the house our children need to move not sit.

- Stock up your pantry with fresh fruits, vegetables, whole grains, dairy and meats. The first step to a healthier lifestyle is cleaning

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

up your homes environment remember your house is a "Living Being" lets make it clean, pure and healthy for our bodies.

For more information please visit the following websites for daily inspiration and motivation to get your journey of

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

a healthy active lifestyle started.

http://theweightingroom.blogspot.com
http://www.theweightingroom.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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E-Articles - The Obesogenic Environment

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