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  • E-Articles - Childhood Obesity

    Childhood obesity is a term that refers to those children and adolescents between the ages of 6 –17 whose body weights are more than 25% fat for boys and 32% fat for girl
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    s. Childhood obesity is reaching epidemic proportions, and if something is not done, children will continue to be more unhealthy and unhappy.


    Obesity in children can
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    lead to a whole host of health problems, many which are not often seen until late adulthood. These include:


    • Diabetes
    • High Blood Pressure
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

  • Heart Disease
  • Asthma
  • Sleep Apnea
  • Greater risk for injury for muscle and bone injury





  • Obesity can also have a
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    profound effect on children and adolescents emotionally as well. Children and adolescents might be teased by their peers, be left out of team sports because of their perc
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ived inability to play, and become depressed because of the lack of clothing available for larger sizes. This can lead to depression, and even binge eating as a means of
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    oping.


    There are a number of factors that contribute to childhood obesity, many of which can be altered with simple lifestyle changes within the family. These inclu
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    de:


    • Lack of exercise or regular physical play
    • Excessive TV watching, video game playing, or computer usage, which encourages a sedentary li
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    estyle
  • Eating too many high fat, high calorie foods
  • and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    enetics
    With the exception of genetics, much can be done to turn around the problem of childhood obesity. Much of it starts within the family, and with
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    the parents. Setting a good example is critical to having children who grow up knowing how to make wise food and fitness choices. Some of the things that parents can do i
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    nclude:

    • Spend time doing physical activities as a family: take walks together, ride bikes together, play games in the backyard
    • Have
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    he kids do chores around the house that require physical exertion, including vacuuming, mowing the lawn, sweeping, and washing the car
  • Give your kids the opp
  • cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    rtunity to participate in sports or other organized physical activities, either at school or in the community, including soccer, swimming, gymnastics, and karate <
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    li> Limit the amount of time the kids watch TV every day
  • Eat meals together regularly, and have the kids help prepare them
  • Limit, or eliminate
  • t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ltogether, fast food stops & Junk foods
  • Reduce the portion sizes at meals and at snack time
  • Avoid buying processed snack items that are high in
  • ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    alories and fat like cookies; opt for fresh fruits, yogurts, or whole grain crackers and bagels
  • Make sure the kids get fruits, vegetables, and whole grains d
  • y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    aily
  • Don’t eliminate treats like cookies or cake entirely; teach moderation, and kids are less likely to overindulge on sweets

  • By setting
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    n example and encouraging a healthy diet and regular physical activity, kids can avoid the trap of childhood obesity. They will be more active, more energetic, happier, a
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    d healthier. And they will be learning habits that will take them from adolescence into adulthood, where they will be able to make smart food and exercise decisions.

    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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