E-Articles - Health and Fitness

Obesity is among one of the most serious problems in the world today. If you consider the hectic life most of us have to go through, many people don't pay much attention to their health and

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eat anything that can fill their stomach to alleviate their hunger. Also they don't perform any physical activity. As a result, obesity has increased mostly in many developed countries. Obes

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ty is not good and has been associated with many health problems. Here are some:

(a) Diabetes
(b) High blood pressure
(c) Hypertension
(d) Haemorrhoids
(e) Heart disease

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s
(f) Heart attacks
(g) Irritable bowel syndrome
(h) Prostate cancer
(i) Colon cancer
(j) Breast cancer

Even though some people are aware of the health hazards of o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

esity, they are oblivious to it. People are busy and don't have much time, even to prepare a meal which lays emphasis on the vital elements of healthy nutrition and excluding fats as far as

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ossible. Being on a diet and paying attention to what you eat plus doing physical activities are two of the most important factors to contributing to a decrease in obesity. To become less ob

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ese, you need to burn fat, calories, be careful to what you eat and lose weight as a result. Here are 2 tips to weight loss success:

(1) Change your eating habits

Don't eat whatever

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you crave. Even if you do, do it moderately from time to time. On the other hand, opt for foods that have high nutritional value but low in fats and sugars as far as possible. Skinless chick

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n or turkey breasts, tuna in brine instead of oil which contain fats, egg whites, oatmeals are some of the types of food that you can incorporate in your daily meals either breakfast, lunch

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

or dinner. Oily fish like tuna have omega-3 fatty acids which can lower the risk of heart diseases.

In addition, don't forget to eat lots of vegetables, fruits and drink at least 1.5 litres

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of water on a daily basis. Vegetables like tomatoes have been proven to be effective against cancer because the lycopene found in tomatoes have powerful antioxidant properties which can prev

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nt cancerous cells from developing or destroy existing ones. Fruits like banana, papaya are really effective against constipation which can lead to problems like haemorrhoids, bowel irritati

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ons and colon cancer.

(2) Be more active and engage in physical activities

Get off the couch or your computer chair and start doing some physical activities. Sweating is good for yo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

because not only it releases toxins from your body but the more your sweat, the less obese you'll become. But don't think that just sitting in the sauna and sweating will make you become le

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s obese and lose weight. You'll be rather losing water and not real sweating to burn fat and calories. Remember no pain no gain.

Rather, try to do some jogging 3 times per week, do some aer

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

obics and use cardio machines like exercise bikes, treadmills and steppers at the gym. Even you don't go to the gym, there are several ways you can exercise at home. You can do some basic ex

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rcises like push ups, sit ups, squats which will make you sweat. If you find most of these activities too strenuous, get in the habit of walking long distances with effort. Walking is a good

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

exercise which can make you really sweat if you do it effortfully rather than leisurely. Also, consider walking instead of taking the car if you're not too far away from your destination. Th

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

is is an additional exercise. With time, you'll be surprised how you'll become less obese with such a simple activity.

Becoming less obese and losing weight is without any doubt achievable

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ith will and determination to succeed in your weight loss goals. So start taking action today, lead a healthy life and reduce the risk of health problems considerably. You'll be glad you did

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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