E-Articles - Health and Fitness

Despite a better perception regarding causes of obesity, the number

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

of obese and overweight people is rising at an alarming rate. Acco

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ding to statistics presented at the 14th European Congress on Obesi

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ty, more than 300 million people worldwide are affected by obesity.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Studies evaluate that obesity rates in Europe have risen 15 percent

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

in the past ten years, while in Japan it has doubled since 1982.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

The big concern among specialists is the astounding numbe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

of obese and overweight children. In the US for instance, the per

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

centage of obese young population has tripled in the past 25 years.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Obesity is no more an aestetic problem. In some West Eur

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

pe countries, up to 8 percent of total healthcare budget is related

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to obesity and its complications. In our days, the obese condition

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

is tightly connected to a number of severe diseases such as diabete

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s, atherosclerosis and other significant health problems that are c

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nsiderate causes of death.

The actual finding that exces

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s weight is going epidemic leads to the conclusion that obesity mus

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

be recognized and treated as a disease with fatal complications. M

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

st of the prevention efforts must target the young population becau

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

se obese condition in children is close associated to certain high

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

isks of developing heart disease, stroke and diabetes in later life

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/261851/e-article-Obesity-A-Disease-With-Deadly-Complication.html">Obesity: A Disease With Deadly Complication</a>

BB link (for phorums):
[url=http://www.e-article.org.ua/article/261851/e-article-Obesity-A-Disease-With-Deadly-Complication.html]Obesity: A Disease With Deadly Complication[/url]

Swimming pools consume more energy than most pool owners realize. Would you leave your refrigerator open all the time? If you are not using efficient, digital pool timers or controls you are throwing money away.

How to learn Reiki and steps to become a Reiki Master. Read here to learn about the three levels of Reiki-

Is it possible to reverse the effects that ensue with steady decline of testosterone levels and sexual performance in middle aged men safely and effectively without the use of hormonal supplements? It is my experience that a new Biofeedback Technology called the Quantum Life System might be the answer.

Tags

Links

E-Articles - Obesity: A Disease With Deadly Complication

Related Articles: