E-Articles - Health and Fitness

Back pain, especially lower back pain, is one of the most common types of pain reported in the U.S. It is probably just as common in many other countries, since it is often brought on by improper lifting techniques or

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

unaccustomed exercise.

Most back pain will resolve itself in two to four weeks, but until it does, what can you do for relief of back pain?

Initial Relief of Back Pain

For immediate relief of sudden back pa

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

in, try lying flat on the floor on your back. Raise your legs and place them on a chair. This position will relieve the pressure on your back. Remain on the floor until you begin to get relief of back pain.

Ongoin

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Relief of Back Pain

In the first weeks, there is a tried and proven regimen for relief of back pain. Using most or all of the following in conjunction with one another will give maximum relief of back pain.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

1. Rest

Most of us naturally resort to rest for relief of back pain. This is good when done in moderation. However, you should not take to your bed and stay there. Relief of back pain depends on as much activity

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s is comfortable. Getting up and moving around can ease the stiffness and hasten the anticipated ultimate relief of back pain.

2. Heat

Heat gives relief of back pain by relaxing the muscles. By dilating the b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

lood vessels, heat improves the flow of oxygen to the affected area, reducing the pain and relieving muscle spasms. Use a heating pad on a medium setting to avoid burning the skin. Apply heat for no more than 20 to 30

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

minutes at a time, since constant heat for prolong periods can negatively impact organs in the abdominal area. Never sleep with a heating pad for relief of back pain.

3. Ice

Ice packs, or cold packs, are ano

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

her part of your regimen for relief of back pain. Ice packs may be as simple as crushed ice wrapped in a towel. Or use an ice bag or professional ice pack. If neither is available, wrap a bag of frozen peas or corn in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

a towel. Ice works in an opposite manner from that of heat. Ice decreases blood vessel size, and reduces the flow of blood to the affected are. In doing this, cold reduces inflammation in the back, and provides relie

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of back pain. Avoid prolonged contact with cold packs. Instead, alternate heat and ice, 20 to 30 minutes each for maximum relief of back pain.

4. Exercise

Relief of back pain must include exercise, especiall

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y stretching exercises. Many people avoid exercise, but physicians recommend it highly for relief of back pain. Stretching exercises reduce stiffness in the back, and may relieve compression on the spine. In addition,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

you will strengthen the muscles while you are healing. Strong core muscles will help prevent future back trouble. Ask your doctor or therapist for exercises suited to your condition.

5. Massage

Massage is im

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ortant for relief of back pain, whether it is administered by a professional therapist or by on of the available massage cushions. Massage can stimulate blood flow to the affected area. It can also relax the muscles,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

giving the desired relief of back pain.

6. OTC Medications

Over-the-counter (OTC) medications are also useful in relief of back pain. Choose analgesic medications such as aspirin or acetaminophen, both of whi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

h are intended for relief of back pain and other similar pain. You may also want to try OTC medications that are spread on the back. Ben Gay, Icy Hot, and Zostrix are examples of topical analgesics that give relief of

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

back pain. If your back pain is accompanied by swelling, consider using non-steroidal anti-inflammatory drugs (NSAIDS) to reduce swelling and give further relief of back pain. Nonprescription NSAIDS include such medi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

cations as Advil, Motrin, Actron, Orudis, or Aleve. Check with your physician to be sure these will not react negatively with any prescriptions you may be taking.

CAUTION: If you continue to have pain after tw

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to four weeks, please see your physician for relief of back pain. See your physician immediately if you have any of these other symptoms:

* Leg pain below the knee

* Leg or groin numbness

* Fever

* Nausea or vomi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ting

* Stomach pain

* Weakness

* Sweating

* Loss of control over bathroom functions

The author is not a trained professional, and provides the foregoing advice on relief of back pain for educational purposes only

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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