E-Articles - Health and Fitness

Save Your Neck The single most common reason for neck pain is poor posture, plain and simp

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

le. Sitting for prolonged periods hunched over a computer, for example, can do it, as can poor sleeping pos

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ture. Many people respond to stress by tensing up their neck muscles, which over time, can lead to neck pai

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n as well as headaches. All of the above can cause painful conditions such as neck strain or even pinched n

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

erves.

Neck strain is most often the result of sleeping in an awkward position. This puts tension on the m

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uscles that run along the back of your neck. If you experience neck stiffness upon waking in the morning, t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

his is most likely what has happened.

A good way to relieve the pain and loosen muscles is to stand under

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a hot shower and lit the water run on the nape of your neck. Press your chin to your chest to stretch out t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

hose neck muscles for about 30 seconds. Then hold your head back, pause, and flex forward again. Now roll y

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

our neck from side to side a few times. This should help to ease the stiffness and pain.

It has been estim

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ated that 70% of all pinched nerves are caused by poor posture. Basically, a pinched nerve means that a dis

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

c that sits between two nerves in the neck has probably been bumped out of place. In addition to the pain t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

hat you feel in your neck, you may also experience some numbness and/or a tingling sensation in your arms a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nd hands. You’ll need to seek medical attention for this one.

Your care giver will likely prescribe neck-s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tretching exercises to alleviate pain and improve your neck’s muscles to keep the disc in place. Something

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

you can do at home? Improve your posture. Be sure that your head doesn’t bend forward too much. When you ar

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e seated in proper posture, you should be able to draw a straight line from your ears to your shoulders on

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

down to the hips.

Below are some additional ideas that you can do at home to help cut down on neck pain:

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

• Take a bath towel and fold it lengthwise. Wrap it around your neck before bedtime.

• Try aspirin, naprox

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

en or ibuprofen to relieve pain and inflammation – use as directed.

• Massage your neck muscles.

• Relax.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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