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E-Articles - 10 Tips To Reduce Migraine Headaches
Migraine headaches must be one of the most debilitating illnesses on earth. If you are a sufferer you will know what I mean. The frequency and severity can vary from person to person but many people still loose 2 or 3 days a month to
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
migraine. Yes, that is lost money in your pay cheque or lost quality leisure time with family and friends.
That intense throbbing pain usually at one side of your head and often accompanied by nausea and/or vomiting completely knoc
That intense throbbing pain usually at one side of your head and often accompanied by nausea and/or vomiting completely knoc
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
s many people of their feet. The lucky ones may get some warning a few days before such as cravings for certain foods like sweets and chocolate or general lethargy. In such cases if you can recognise these warning signs it may be pos
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
sible to eliminate the cause or start treatment before the onset. Other people will have what is known as an "aura" for a short time before the migraine kicks in. The most common symptoms of the "aura" are flashing lights in front o
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
your eyes or zig zag lines disrupting your vision. More disturbing symptoms which can occur are numbness down the side which is effected my the migraine or speech difficulties i.e. slurring etc.
There are many triggers which can br
There are many triggers which can br
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ng on an attack. In this day and age probably the most common cause is stress in the work place, the feeling of being constantly placed under pressure can cause great anxiety thus fuelling the migraine.
Certain foods may also be to
Certain foods may also be to
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
blame such as cheese, chocolate, alcohol - red wine in particular, and processed or canned foods which often contain monosodium glutamate. On the other hand lack of food can also act as a trigger.
Strong smells such as perfume, pain
Strong smells such as perfume, pain
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
, stale smoke or being in a stuffy atmosphere often contribute.
To be truthful it takes more than one of these factors to trigger an attack and the combination is unique to each individual.
Before you can think about how to tackle
To be truthful it takes more than one of these factors to trigger an attack and the combination is unique to each individual.
Before you can think about how to tackle
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
the symptoms, prevent or reduce the severity of attacks it is important that you work out what the combination of factors is that may bring on the headache. Try keeping a diary of foods consumed, dates when you felt under increased s
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ress, and so on to gradually build a picture or pattern of events leading up to attacks.
For women (who incidentally are more likely to suffer from migraines than men) it is important to keep track of your monthly cycles as hormonal
For women (who incidentally are more likely to suffer from migraines than men) it is important to keep track of your monthly cycles as hormonal
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
changes in the body before and during your monthly period are often the trigger. The contraceptive pill and hormone replacement therapy can also sometimes increase the occurrence of migraine.
So, you have established the cause what
So, you have established the cause what
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
do you do now?
There are a great many "over the counter" drugs designed to relieve the symptoms, both pain and nausea, however in sever attacks these may not be enough. Prescription drugs from a doctor may be more effective and can
There are a great many "over the counter" drugs designed to relieve the symptoms, both pain and nausea, however in sever attacks these may not be enough. Prescription drugs from a doctor may be more effective and can
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
sually be tailored more to suit individuals.
However, lots of sufferers these days would rather not take drugs but rather try other methods usually aimed more at prevention rather than cure.
There are a few things you can try. Here
However, lots of sufferers these days would rather not take drugs but rather try other methods usually aimed more at prevention rather than cure.
There are a few things you can try. Here
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
are some examples:-
1. Try different methods of relaxation for instance; yoga or meditation, going along to one of these classes may turn out to be fun! Alternatively you can teach yourself these techniques using books or DVDs
2.
1. Try different methods of relaxation for instance; yoga or meditation, going along to one of these classes may turn out to be fun! Alternatively you can teach yourself these techniques using books or DVDs
2.
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
nsure you get enough sleep most people need between 7 and 9 hours per night.
3. Take some form of exercise for example walking or swimming - nothing too excessive because too much exertion can bring on a migraine!
4. Set aside at l
3. Take some form of exercise for example walking or swimming - nothing too excessive because too much exertion can bring on a migraine!
4. Set aside at l
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
ast one hour a day just to do something you enjoy which will relax you such as reading a book, watch your favourite television show, do some gardening - fresh air can work wonders after a day at the office!!
5. Eliminate foods from
5. Eliminate foods from
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
your diet completely which you have established act as triggers for the headaches. Have some fun trying out recipes using alternatives.
6. A gentle massage can be very effective and other more alternative treatments appear to help i
6. A gentle massage can be very effective and other more alternative treatments appear to help i
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
some cases such as acupuncture.
7. If you have an attack try lying in a darkened room and place an ice pack at the back of your neck - for others a hot water bottle may be more effective.
8. Apply gentle pressure to the painful ar
7. If you have an attack try lying in a darkened room and place an ice pack at the back of your neck - for others a hot water bottle may be more effective.
8. Apply gentle pressure to the painful ar
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
eas of your head and if possible sleep.
9. There are herbal medicines that can be taken as preventative measures such as feverfew and butterbur or supplements containing magnesium and vitamin B2. If you suspect or are pregnant or br
9. There are herbal medicines that can be taken as preventative measures such as feverfew and butterbur or supplements containing magnesium and vitamin B2. If you suspect or are pregnant or br
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ast feeding do not use any of these items without professional advice.
10. The most important thing to remember when trying to prevent or reduce migraine attacks is to eliminate one or more of the contributory factors - the triggers
10. The most important thing to remember when trying to prevent or reduce migraine attacks is to eliminate one or more of the contributory factors - the triggers
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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