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When one hears the words physical therapy, what most likely comes into mind are masseuses. Yet physical therapy delves much deep

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

er than your typical run-of-the-mill masseuse. The benefits of physical therapy far outweigh those of regular massages from untr

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ained masseuses. What physical therapy is – is a science. It’s a far cry from the indiscriminate kneading and pounding of some m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

asseuses. They only make you feel better for awhile, sort of like a placebo. One of the benefits of physical therapy compared to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

massages is that physical therapy cures you.

There are virtually hundreds of benefits of physical therapy, but the key benefit

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

are to evaluate physical problems, increase and maintain muscle strength and endurance, restore and increase joint range of mot

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ion, increase coordination, decrease pain, decrease muscle spasm and plasticity, decrease swelling and inflammation of joints, p

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

romote healing of soft tissue lesions, prevent contracture and deformity of limbs, alleviate walking problems, educate patients

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and family, decrease stress and a whole lot more too numerous to mention. These are but a few of the benefits of physical therap

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

y.

Regular massages from untrained individuals may prove beneficial in some ways, but in the long run and more bang for the buc

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

, physical therapy very much eats the competition for lunch. The benefits of physical therapy depend greatly on the treatment me

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

thods that physical therapists utilize. Some examples are joint mobilization, soft tissue release, trigger point release, manual

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

therapy, myofascial stretching, muscle re-education, modalities, therapeutic exercise, re-conditioning program, specific streng

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

thening of weak muscles, and a home exercise program to name a few. These methods are not only far superior to indiscriminate kn

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

eading and pounding, but proof of the scientific nature of physical therapy. The benefits of physical therapy are not only for i

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nstant gratification in terms of comfort, but the benefits are a long term solution for afflictions, a lasting cure for those wh

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

need it.

I am reminded of a friend who had a sore back. Instead of seeing a physical therapist, he went to a masseuse for inst

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ant relief. He did get instant relief, but after a few days, his spine grew worse and now walks with a permanent limp and crooke

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d back. He himself says that he should’ve gone to a physical therapist and regrets not having gone. This is a perfect, if tragic

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

example to the benefits of physical therapy, and the pains and risks of leaving your health in the hands of untrained masseuses

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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