E-Articles - Health and Fitness

According to the Chinese folklore, in 2737 BC. Chinese emperor Ksan Nung found the tea beverage while he was drinking a glass of hot water. The wind dropped into the glass a leaf from the tree under which the emperor was sitting. He found the concoction to be a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

great improvement from plain boiling water. And after this he gave orders for growing teas.

Today, tea has hundreds of species in different genera and is a popular thirst quencher and the most commonly consumed beverage in the world after water. The Chinese a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

d Japanese have a habit of drinking the beverage in the afternoon and the British people drink several cups of it every day. Tea-drinking is national pastime in India, where the biggest production of the plants is. Green tea herb is especially liked by people f

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rom Far East, and the semi-fermented tea, especially the oolong (black dragon) by people of south China and Taiwan. Black tea is consumed relatively more in Europe. Beyond its taste for enjoyment, tea is packed with various health perks. It contains anti-cancer

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

polyphenols, essential oils, some vitamins (E and some from B group) and minerals, including a high percent of zinc which is important for pregnant women. The more processing tea leaves undergo, the darker they become. Green tea, the least processed tea, is sim

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ly steamed quickly. Black and red teas are partially dried, crushed and fermented.

Tea has long since been associated with nearly every meal in many countries and accepted as a healthy supplemental drink. Scientific studies suggesting that medical benefits of

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tea can improve a person's health have sparked new interest in tea as an alternative drink. A cup of tea contains an average of 40mg of caffeine, compared to 85mg as found in a cup of freshly brewed coffee. The heart-health and cancer-preventive benefits of bla

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

k and green teas are well-publicized. Scientists point to a natural class of antioxidants called flavonoids found in many natural plant-derived foods, including tea. These antioxidants help remove the body of molecules called free radicals, which are body damag

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ing by-products from pollution and the natural aging process. Free radicals in the body's cells are very unstable and tend to react negatively with other important molecules like DNA, causing malfunctions and damages on the cellular level. The destruction of th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

se free radicals paves the way for many diseases including cancer. It is also believed that antioxidants have positive effects on dental health. Studies showed that rinsing the mouth with black or green tea may prevent cavities and gum disease. The antioxidants

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

in black tea inhibit the growth of bacteria that promotes cavities and affect their ability to attach to tooth surfaces. Research suggests that tea may also increase bone-mineral density and drinking tea regularly for years may produce stronger bones. It also i

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ndicates that older women who are tea drinkers are less likely to develop rheumatoid arthritis than those who do not drink tea. Tea drinkers may be surprised to learn another health benefit of tea: blood pressure control. Drinking a half-cup of green or oolong

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ea per day could reduce a person's risk of high blood pressure according to some studies.

Many people use honey to naturally sweeten tea in replacement of table sugar due to its associated health benefits. A good source of carbohydrates, natural honey sweetens

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

with no additives or preservatives. Because of its composition, pure honey has a lesser effect on glucose and insulin levels. Both tea and honey are known to contain antioxidants, which help prevent damage to cells and tissues that contribute to diseases like

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ancer.

Personally I am very fascinated and intrigued by how the hundreds of varieties of honey can mix and match with these tea blends to customize and suit personal moods and preferences in taste. I cannot imagine the kind of exciting impact these multiple co

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

binations would have on our sensory experiences, and not to mention the natural health benefits inherent in both products. We don’t have to be a connoisseur to experiment the various honey-tea combinations. It’s fun and easy, just incorporate it into each morni

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ng’s breakfast, afternoon snack, or family party. For instance, avocado honey variety can go with Earl Grey tea, and clover honey with either lemon or mint tea for a unique taste, Tupelo honey variety with jasmine tea, and eucalyptus honey with Irish Breakfast

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ea. Blueberry honey’s pronounced taste adds zest to mild tea blends such as Earl Grey or English Breakfast. Orange blossom honey, one of the most versatile varieties adds a new dimension to most tea blends. Some think it’s best with black teas such as Ceylon an

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d Darjeeling. Teas with strong distinctive tastes, such as Jasmine or Apple cinnamon, go well with mild-flavoured Alfalfa honey. Sage honey, yet another mild variety complements intense tea flavours including orange spice, lemon, and mint.

So, why not consider

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

including 1-2 cups of tea as a healthy part of your daily diet. The flavour possibilities are endless and perhaps limited only by your imagination. Lastly, remember, when adding honey into tea, wait till it’s not too hot to avoid destroying its natural goodness

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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