E-Articles - Health and Fitness

The Atkins Nutritional Approach™, as the Atkins diet is commonly known, has worked for several people with weight problems, although the opinion about its efficacy, especia

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

lly in the long term, is divided among the medical community. Considerable controversy surrounds the program. Most other diets, and there are numberless of them out there,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

follow the principle of avoiding high-fat foods. But the Atkins diet allows things like red meat, bacon, butter, cheese, eggs and so on, which are all high in fat. Yet, to

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the utter surprise of everyone who repose their trust in the tried and tested low-fat diets, the Atkins diet works.

The reason is rather simple. The Atkins diet limits the

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

consumption of foods containing large amounts of carbohydrates, such as rice, pasta, white bread, cereal and sugar. Your body burns its excess fat during a process consist

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ing of four phases, which the late Dr. Robert Atkins developed. In his book Dr.Atkins New Diet Revolution, published in 1972, he advised dieters to cut down on only carbohy

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

drates, not both fats and carbohydrates as had been the practice followed until then.

During the first phase of Atkins diet, the dieter is allowed to eat only very small q

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

uantities of carbohydrates. The carbohydrates allowed are limited to a maximum of 20 grams per day, in the form of salads, or vegetables without starch.

The second phase a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

llows the dieter to progressively increase the amount of carbohydrates by 5 grams (from the initial 0 - 20 grams in the first phase to 25 grams in the first week of the sec

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ond phase) a day. Thereafter, as long as the dieter loses weight, the weekly increase of 5 grams of carbohydrates continues. Once the dieter reaches a stable weight, he has

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

to reduce the carb-intake by 5 grams, so that he remains at the weight reached.

The purpose of the third phase is to help the dieter to maintain the weight reached at a s

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

teady level, if necessary, by increasing the intake of carbohydrates at the rate of 10 grams per week.

The fourth and final phase allows consumption of more foods of a wid

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

er variety, even though the carbohydrate consumption remains restricted. The idea is to maintain over a long period of time the weight reached in the earlier phases.

The q

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

uestion about how exactly the Atkins diet works for weight loss can be answered either by referring to complex scientific processes like lipolysis and gluconeogenesis and s

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

o on or by using simple and direct explanation that may be easier to appreciate. When the body is starved of carbohydrates, which provide quite a bit of the energy required

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to run its various systems, it turns to its stored fat and burns it to replenish the energy deficit. As more and more of the stored fat is burnt to supply energy to the bo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

dy, more and more weight is lost. Another thing is that by controlling the amount of carbohydrate-intake in the body, the Atkins diet controls the quantity of insulin in th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e body. Being a storage hormone, insulin converts carbohydrates into sugar and stores it as fat in the body, in the normal circumstances. However, when the quantity of carb

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ohydrates is lower than normal, the sugar in the body is not stored in the shape of fat, but burnt instead. Again, the result is weight loss.

Atkins has become popular for

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

two reasons. One is that it works, especially when exercise goes with it. Two, it gives the dieters the freedom to eat the foods that are prohibited in other diet programs

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.e-article.org.ua/article/262461/e-article-How-Atkins-Works.html">How Atkins Works</a>

BB link (for phorums):
[url=http://www.e-article.org.ua/article/262461/e-article-How-Atkins-Works.html]How Atkins Works[/url]

There are a number of views on what exactly wealth is, but it usually is the ability to allocate resources to yourself and the ability to save time and resources of your choice. This can be a bit confusing so I would suggest that you just know that wealth is the concentration of resources, including time.

Credit cards! If you’re like most people, you probably love them some times and hate them other times. They can be a great way to manage your finances and they can be a terrible bill to get every month.

Supplements must be taken with doctors' prescription and according to one's diet and nutritional needs.

Tags

Links

E-Articles - How Atkins Works

Related Articles: