E-Articles - Health and Fitness

The Mediterranean diet has always been very popular. It’s a diet that is styled after the eating habits of peopl

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e of the Southern Mediterranean region. eDiets have created a Mediterranean plan and added it to their extensive

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

diet selection. The Mediterranean diet is generally high in the consumption of fruits, vegetables, breads and ce

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

eals; potatoes, beans, nuts, and seeds; olive oil, and monounsaturated oil with many demonstrated benefits, is t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e main source of fat and a major source of antioxidants. Dairy products, fish, and poultry are maintained in low

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

moderate amounts and red meat consumption is negligible. On average fish is eaten 3 times a week, increasing th

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Omega 3 fatty acids content in the Mediterranean diet. Eggs are eaten 0-4 times a week and wine is consumed in

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ow moderate amounts.

Mediterranean style diets closely resemble the American Heart Association dietary guidelin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s. However, Mediterranean diets contain a high percentage of calories from fat which can contribute to obesity.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

What Are the Basics of the Mediterranean Diet?
• Eat lots of fresh fruit and vegetables.
• Cut

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

down on red meat and processed foods.
• Increase healthy fats (olive oil, fish, nuts, etc)
• Health im

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rovement – lower chances of heart disease and cholesterol.

A Diet for Good Health
The people of the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Southern Mediterranean have a lower rate of incidences of heart disease than many other Western countries – and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

their death rates are also lower. Many believe this is the case due to the low levels of saturated fat in the di

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

t. In a Mediterranean diet olive oil (a monounsaturated fat) is the primary source of fat in the diet.

Medit

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

rranean Diet Plans and Recipes

Sample Meal Plan

• Yogurt with fruit and nuts
• Pasta salad and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

fruit
• Salmon with roast vegetables
• Crackers and hummus

There are numerous cook books and other bo

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

oks available for Mediterranean style cooking; also the Sonoma Diet is considered to be the new Mediterranean di

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t. The great thing about this kind of diet is that the people who go on this plan enjoy the food. This is a very

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

good diet and comes recommended however the Sonoma Diet is a better version of this style of weight loss program

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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