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Diabetes is a fast –spreading epidemic. It is afflicting people irrespective of their cast, creed or age. Statistics published by the National Diabetes Info

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rmation Clearinghouse reveals that almost 20.8 million [roughly 7% of the population] suffer from diabetes.

Research has shown that diabetes is a life-styl

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

disease. Most people, living in the twenty-first century, live a fast paced life. The daily pressure of deadlines, stress, the consumption of processed foo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ds and the lack of wholesome meal has meant that more and more people are now falling victims to diseases like obesity and diabetes.

The medical fraternity

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

on its part is trying to find out ways to find a cure and prevent the occurrence of such diseases. Doctors have realized that diet can prove an important al

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ly in fighting diabetes and obesity. Large minor changes and a few major changes can go a long way in preventing the occurrence of life-style related diseas

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s. In fact, a few doctors have come out with their own diet plans. The South Beach diet is one of them. This phenomenally successful diet is formulated by D

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r. Arthur Agatston. According to Dr. Agatston, the South Beach Diet can truly become a lifestyle. Weight loss can be sustained and the manifestations of pre

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

diabetes and, often, of type 2 diabetes can be reversed.

South Beach diet clearly demarcates the entire gamut of food products based on good and bad carboh

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ydrates.

Glycemic index is used to categorize carbohydrates as good or bad. The glycemic index is a dietary index that's used to rank carbohydrate-based fo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ds. The Glycemic Index predicts the rate at which the ingested food will increase blood sugar levels.

According to ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

achdietclub.com/sbdclub/south-beach-diet-phase-three.html">South Beach diet, the consumption of bad carbohydrates to be avoided as it causes an upsurge

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

in the release of insulin as well as makes one feel hungrier. This leads to over eating and subsequent weight gain. Weight gain makes one more vulnerable to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

diabetes. Hence, South Beach diet suggests that to remain healthy avoid bad carbohydrates from reaching your food plate.

However, many are skeptic about th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e South Beach diet’s ability to control diabetes. The American Diabetes Association does not approve of glycemic index. It is of the opinion of that glycemi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

index plays a little role in weight –control. Rather it is the amount of carbohydrates that directly affects weight.

Others are of the opinion that whole

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

grain breads and fruits do not contain god carbohydrates. According to Dr. Mercola, those sensitive to carbohydrates, subclinical gluten, or find it difficu

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

t to control their insulin levels, should view the intake of fruits and grains as a recipe for disaster. He also criticizes the recommendation of artificial

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

sweeteners by Dr. Agatston. Dr. Mercola says that past studies have shown that artificial sweeteners increase the incidence of diabetes, cancer etc.

Thus,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

as far as diabetes is concerned some are of the opinion that South Beach diet does aid in control and prevention of diabetes whereas others remain skeptical

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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