E-Articles - Health and Fitness

Two questions among many have plagued me when it comes to dieting. Are carbohydrates addictive and do they change our bodies over time?

I propo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

se this answer; absolutely yes.

In my case, I have never liked vegetables and could never get past the awful taste that they made in my m

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

outh. I don't care who made them; my mother, grandmother, friends mothers or even restaurants. Green beans are the nastiest tasting things I ha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ve ever put in my mouth. This also includes squash, turnips, spinach, sweet potatoes, etc., etc., and etc.

Notice that I did not mention corn o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lettuce. Corn is high in carbs but unfortunately it is one of the only grown crops that I like. And thankfully, lettuce (which is mostly water

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

) is on the carbs good list of good foods to eat.

So what else is on a Carbs good list of vegetables to eat? Broccoli, Cauliflower, Cabbage, Cu

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

cumber, Celery, Zucchini, Squash, Radishes, Bean Sprouts, Spinach, Collard Greens, Asparagus, Eggplant, and Peas. WOW! That's quite a list exce

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t they are too nasty for me. Not one of these has a palatable taste for me to enjoy.

So where does this leave people like myself? Hamburgers,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

hotdogs, pizza, tacos, barbeque, etc, etc, and etc. Basically, anything sold in Fast Food.

Now all of this leads to my next question. Do Carbo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hydrates change us? Do we become dependant upon carbs? I believe the answer is yes. Combined with Sugar this becomes a powerful drug. Now I d

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

not have any scientific proof except my own diet. But I can honestly say. Eating non-carb based food still leaves a desire in my system for pe

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

anut butter, candy bar, and even honey buns. McDonalds, Hardy’s, Wendy’s, Captain D's and your favorite restaurant still pull at me when I drive

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

by.

It is like my system has been forever changed. The withdrawal for me is great. I have lost a total of 70 pounds and I was doing pretty we

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ll but the temptations finally got the better of me. I would sneak honey buns, pop tarts, and other items after the family went to bed. It sati

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

fied a temporary craving but the damage was still there.

Yes I fell off the wagon for a short time but I am back on. I only gained back 20 poun

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ds but I am re-living the pain of withdrawal while I re-loss the 20 pounds that I gained.

Thank goodness meat was not eliminated. Most definite

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ly Beef, Chicken, and Pork will stay on my plate.

So my point is this. The struggle of weight loss is going to continue to be there. Food is a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

dictive because our bodies need it to survive. We just have to be smarter than our cravings. I have a very boring diet now but I am losing weig

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ht. I am searching for food combinations that taste better and they are coming about. I just have to look for them.

So if you and I think that

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

we can go back to our old ways of Fast Food and Restaurants then we are lying to ourselves. Keep the faith and continue to build upon your diet

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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