E-Articles - Health and Fitness

Liquid diets are usually a temporary form of diet advised before a surgery tak

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

es place. The liquid diets fall in to two categories. One is a low calorie liq

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

uid diet and the other a meal replacement liquid diet.

The low calorie liquid

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

diet is practiced under strict medical supervision only. This diet provides on

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

an average about five hundred to eight hundred calories a day. This is normal

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

y a short-term diet plan, mostly recommended to those who have serious obesity

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

problems and need to lose a lot of weight in a short span of time.

The meal

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

replacement liquid diet replaces one or two whole meals with liquids. This typ

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of liquid diet is offered to many people as an effective tool to reduce weigh

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t.

A liquid diet consists of fresh fruit juices or shakes. They are prepared

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eeping in mind nutritiously, along with sweeteners, sugar, skimmed milk and a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

good quantity of fiber, minerals and vitamins. Certain liquid diets also permi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t the consumption of solid or real food intake in proportional sizes.

There c

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

uld also be certain disadvantages an individual encounters while on a liquid d

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

iet. The person may get very little fiber, and the important antioxidants pres

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nt in whole fruits and grains may be left out. This will lead to having a low

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

resistance to disease. Moreover, a liquid diet should be under medical supervi

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

sion only. The weight lost during the intake of a liquid diet is rarely mainta

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ned, as such diets do not teach us to eat right long term. An individual shoul

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

d realize, that although liquid diet works, it is not recommended for everyone

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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