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What is a Low Carb Diet? You'll do away with bad carbs and bad fats, and start eating good fats and good carbs. What you need to understand is that you are not really on a die

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t, but changing the way you eat. Eating the wrong foods consistently throws your body out of balance. Most of us tend to overdue it eating processed carbs. What do I mean by p

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ocessed carbs? Basically, there are two kinds of carbohydrates, simple and complex. Some refer to them as bad and good carbs, fast and slow digestion carbs and others. Here are

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

some basic explanations:

SIMPLE CARBS - Foods with simple or refined carbohydrates most often have a low nutrient content and a high-glycemic index. They are metabolized quickly

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

(quick to digest). They enter the bloodstream and rapidly elevate blood sugar levels, then fall dramatically within a short span of time. In order to keep the body running healt

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

hy and stable, it is recommended that these type foods be limited. Examples of these simple or overprocessed carbs are white bread, potatoes, and sugary treats like cookies, cand

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

, cupcakes and cakes, and beverages like cola products.

COMPLEX CARBS - Foods with complex carbohydrates contain many nutrients and have a low- to moderate-glycemic index. Highe

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

fiber content in these foods means slower digestion, which is healthier for the body (including reducing mood swings and food cravings). And these foods are considered good choi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

es by health advisors. Examples of these complex carbs are whole grains, most fruits and vegetables. Legumes, plants of the pea or bean family, are also in this category.

WHICH

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

IS BEST?? Studies show that low-carb diets can help with weight loss; which means that the carbs need to be of the complex, low-glycemic type. The key is eating whole, real, unpr

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

cessed food found as close to nature as possible.

WHY DOES YOUR BODY NEED CARBOHYDRATES ANYWAY? Carbohydrates cause your body to produce a hormone called Insulin. Insulin is re

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ponsible for the movement of glucose (sugar) from the food you eat into the cells of your body to be used for energy. Excess glucose (that is not burned as energy) is then stored

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

as body fat.

Years of consuming too many carbohydrates can lead to a sensitivity of the cells to Insulin. This can result in the body having to make more (and more) Insulin to g

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

et the same job done. Over time over-production of Insulin can lead to high cholesterol, heart disease, obesity and type II diabetes and more. A side effect of Insulin over-produ

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tion is that it actually causes more fat to be deposited.

EATING LOW CARBS WORKS WITH YOUR BODY.

All the food you consume provides energy for your body. Your body burns fuel in

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

this order: carbohydrates / fat / protein. So, by limiting the carbohydrates you eat, it is perfectly natural for your body to burn fat next. Your body will go inward and start

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

burning your own body fat for fuel. Because of this store of body fat, you wont feel hungry and you will maintain a more even blood sugar level throughout the day.

One important

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

thing to note here is ... it is not eating too much fat that makes you overweight - it is eating far more carbohydrates than your body needs to use for energy.

It is important,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

however, that any and all dietary planning should be made under the guidance of your own medical practitioners. Also, drinking 8 glasses of water a day and consistent exercise is

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

vital to your body's health. This content only presents overviews of low-carb research for informative purposes and does not replace medical advice from a professional physician

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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