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Generally when one thinks of skin parasites, they think of scabies and ring worm for which the medical profession is well equipped.

Unfortunately I contracted the types of skin parasites about which doctors know nothing. I was doing my yearly back yard Spring

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

clean-up when it happened. As I pulled a strangulating vine from a tree I noticed a cloud of dust descending upon me. I disposed of the vine, decided to call it quits, and took a shower thinking no more of the dust cloud.

My profession is about managing stre

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ss and the use of hypnosis for eliminating unhealthy habits. Within a month my life changed to the point that I was on the brink of anxiety panic attack.

Two days later while visiting my mother; my lady friend, Fran, and I began itching all over our bodies. W

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e immediately left for home and took hot baths which provided relief. But within hours we were both itching again. The next few days were horrendous and confusing as we used everything we could to get rid of them--anti itch creams, rid, Nix...

I deduced the s

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

urce of the infection was that cloud of dust but that did little good. Soon we realized that our bedding was contaminated and we began laundering our bedding daily with bleach. We took scalding baths two-to-three times per day to control the itching and biting

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

. And then we realized that the bugs were all over the house-on the furniture, in the rugs… Thinking it must be some kind of mite, I ordered diatomaceous earth and dusted it all over the house.

Realizing how prolific the mites were, I treated my front and re

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ar yard and all the shrubs with an insecticide that kills jiggers.

Fran went to her doctor who found nothing and at her urging he prescribed Elimite. We both used it thinking life would soon be normal only to find that within four days all symptoms returned.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

I went to a dermatologist who after observing all the bites and rashes, took a plug sample for analysis and prescribed antibiotics along with Diprolene. Again we had about four days of relative freedom and then all symptoms returned. My doctor called to infor

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

me that the analysis of the plug sample showed nothing.

I tried everything I could think of--boric acid, sulfur… I mixed sulfur with Vaseline and applied it to my skin. I looked like I was jaundiced with liver disease; my silver hair was yellow. I noticed t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hat my arms sparkled in sun light-maybe the eggs of the parasite.

After about three months of living in this hell. I experimented with approximately 30,000 mg of garlic and found that the symptoms stopped. After a few days I thought I was cured and stopped t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

he garlic only to have the itching and biting return within days.

Fran moved away and got rid of her infestation with a product called Liquid Needles and ice baths. I could never bring myself to an ice bath and the Liquid Needles were like a band aid.

I reli

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ed heavily on garlic and eventually was at about 200,000 mg per day-I was popping those little round capsules like candy. I really didn't notice any garlic odor about me so my body must have been using all the garlic or I was oozing it from my pores and was ob

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ivious to it.

Ultimately I confided in a friend who suggested that I experiment with diet-an alternative to garlic. I began only eating eggs and within a day all symptoms of itching and biting had subsided. Life can get boring with only eggs so I began adding

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

one new food at a time. I found that anything with wheat or oat flour caused symptoms to return. Rice was safe. Fruit was a big problem. The next couple years was about experimenting with various foods.

Eventually I found an old-timer doctor who was familiar

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

with bird mites. He prescribed ORAP which along with the diet enabled me to eventually expand my diet to what I identify as Stage II of the diet. The ORAP was stopped after ten weeks and I remained on Stage II of the diet for nearly ten years during which tim

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e I got married, had normal intimate relations, and was free of being contagious as long as I remained on Stage II of the diet.

Over the years I helped dozens of other sufferers rid themselves of the symptoms with the diet. I also found that the itching and b

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ting symptoms can be caused by several different organisms:
• Nematodes such as Strongyloides stercoralis
• Morgellons
• Collembola (spring tails)
• Fungi
• Mites

I also learned that Lyme and Protozoan infections often accompany t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

he parasites compromising one's immune system further complicating any attempts at treatment. And what's more frustrating is that the Lyme and Protozoan are not easily diagnosed except for special labs such as Bowen Labs in Florida and Igenix in California.

I

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

learned that there are diagnostic tests for some of parasites but with most of them there are no diagnostic procedures much less treatment.

All of what I've learned is in an e-book, Soothing the Itch Within and the Diet to Control It. It has all the specific

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s of the diet, disinfection and bathing protocols, medical approaches including transcripts with specialists in the field, alternative approaches-rifing, ionic minerals, bentonite clay, faith healing--a chapter of testimonials, treatment of Lyme, Protozoan

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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