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E-Articles - Warts and Wart Removal Methods
Warts are small, usually harmless and painless growths on the skin caused by a virus. The virus is called human papillo
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
mavirus (HPV) that resides in the bottom layer of the skin. Different sub-types of HPV cause different kinds of warts.
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
People of all ages, but most commonly children and young adults, are prone to getting warts. They are spread by direct
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ontact, simply by touching the wart. Warts can sometimes be contagious, but transmission from person to person is uncom
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
mon. However, warts can be embarrassing and disfiguring, and sometimes itch and hurt.
There are different types of war
There are different types of war
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
s. Common warts usually appear on the hands, and flat warts are found on the face and forehead. Genital warts are found
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
on the genitals; plantar warts on the soles of the feet, and subungual warts and periungual warts appear under and arou
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
nd the finger nails or toe nails.
While some warts cause no discomfort, some are difficult to treat, some disappear wi
While some warts cause no discomfort, some are difficult to treat, some disappear wi
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
hout treatment and others do require treatment.
In some cases, over-the-counter medication can remove warts. The medic
In some cases, over-the-counter medication can remove warts. The medic
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
tion is applied to the warts daily for several weeks. For plantar warts that are found on the soles of the feet, specia
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
cushions are available at drugstores. These are pads that help relieve any pressure and pain from the warts. For the r
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
emoval of persistent warts, prescription medication may be required such as surgical removal or removal by freezing, bu
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
ning or laser treatment.
Freezing, which is also known as Cryotherapy, is a method by which liquid nitrogen is applied
Freezing, which is also known as Cryotherapy, is a method by which liquid nitrogen is applied
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
either as a spray or on a cotton swab to the wart which freezes and kills the effected cells. Although the lesion heals
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
without significant scarring, a blister does form on the area. If the wart is on the foot, this kind of treatment is n
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
t the first choice, because it becomes very painful to walk. Another option is Immunotherapy which triggers the immune
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ystem to destroy the virus that causes the wart. However, since the substances used are expensive, sometimes dangerous
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
and require special handling, they are used as a last resort when all other options fail.
Most wart treatments are suc
Most wart treatments are suc
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
essful and the warts disappear for good. The body's immune system also gets rid of any tiny bits of wart that might be
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
eft behind. In some cases, should the warts come back, it is best to seek medical advice on other ways of treating them
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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