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E-Articles - Keep Your Skin Healthy With Chiral Skin-Care Products
If you want to be healthy, there are many things you can do to achieve this. Good exercise, a good diet, proper rest and a positive attitude about life are important practices for good health.
And if you want the world to see how healthy you are, there are of course many ways that you can show your health to the world.
The most obvious way
And if you want the world to see how healthy you are, there are of course many ways that you can show your health to the world.
The most obvious way
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
is of course your skin.
So, how do we keep our skin healthy?
One popular, new method is the use of cosmeceuticals. That may sound like a strange word. According to Robert A Schwartz, MD, Professor and Head of Dermatology at UMDNJ-New Jersey Medical School, “Cosmeceuticals represent a marriage between cosmetics and pharmaceuticals.”
He not
So, how do we keep our skin healthy?
One popular, new method is the use of cosmeceuticals. That may sound like a strange word. According to Robert A Schwartz, MD, Professor and Head of Dermatology at UMDNJ-New Jersey Medical School, “Cosmeceuticals represent a marriage between cosmetics and pharmaceuticals.”
He not
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
es that, “Like cosmetics, (they) are topically applied, but they contain ingredients that influence the biological function of the skin.”
They don’t just work on making your skin look pretty, blemish free and all that. Rather they improve skin appearance by putting healthy nutrients in the skin. Or, in other words, cosmeceuticals make the sk
They don’t just work on making your skin look pretty, blemish free and all that. Rather they improve skin appearance by putting healthy nutrients in the skin. Or, in other words, cosmeceuticals make the sk
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
in look healthy because it IS healthy.
If cosmeceuticals is a new word for you – and perhaps a new concept – then let me add another important term, in this discussion about skin care.
That’s Chiral Technology.
When you use natural ingredients for skin care, you still need to make sure that your skin can use what it’s being ‘fed’.
Chiral
If cosmeceuticals is a new word for you – and perhaps a new concept – then let me add another important term, in this discussion about skin care.
That’s Chiral Technology.
When you use natural ingredients for skin care, you still need to make sure that your skin can use what it’s being ‘fed’.
Chiral
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
technology is simply a process of purification. It extracts the purest form of positive molecules and eliminates the negative molecules (that can cause damage and irritation) out of the natural ingredients you use. It thus provides the proper fit onto the skin's receptors for repairing and maintaining healthy skin with less irritation.
It se
It se
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ems to be one of the newest concepts and practices for healthy skin and healthy skin care.
So, how does Chirality (as it’s called) work?
Chiral molecules are exactly the same in every way. Like your hands, they are perfect mirror images of each other. So, in a way, they are exact opposites! An example is amino acids. Our body uses just left
So, how does Chirality (as it’s called) work?
Chiral molecules are exactly the same in every way. Like your hands, they are perfect mirror images of each other. So, in a way, they are exact opposites! An example is amino acids. Our body uses just left
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
-handed amino acids (you will notice on your protein formulations words like L-proline). The right handed ones are out there in the world, but the body cannot use them.
So, what does this have to do with skin care?
The body's receptors are all chiral. They are like gloves made to fit only over the correct hand. Thus a good skin care product
So, what does this have to do with skin care?
The body's receptors are all chiral. They are like gloves made to fit only over the correct hand. Thus a good skin care product
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
should be formulated in a chirally correct way. Or in other words, the product would be a proper fit on to the skin's receptors. If the product is chirally correct, then any skin treatments, whether from professionals or at home, would provide the most effective therapy for repairing the skin.
Chiral technology makes it possible to produce
Chiral technology makes it possible to produce
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
a product that is better than “natural” because it separates the molecules, allowing us to remove the undesirable side of the molecule and use only the desirable one.
As I noted, chirality refers to molecules that fit ‘like a glove’ with the skin’s receptors. But what happens if the wrong-handed molecule is used?
A good example of this is T
As I noted, chirality refers to molecules that fit ‘like a glove’ with the skin’s receptors. But what happens if the wrong-handed molecule is used?
A good example of this is T
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
halidomide--- the morning sickness drug given to pregnant women in the late 50s and early 60s. The drug company knew of this drugs chirality, but did not investigate the real consequences. On one hand the morning sickness was eliminated and on the other hand it caused terrible side effects and severe birth defects. If chiral technology had be
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
n applied this would have been eliminated.
But, though chiral technology is certainly one of the newest concepts in skin care, the technology itself has been around for awhile.
In fact, Louis Pasteur discovered it in 1848 while studying tartaric acid from wine making. He found two tartaric acids on the exact mirror image of the other like o
But, though chiral technology is certainly one of the newest concepts in skin care, the technology itself has been around for awhile.
In fact, Louis Pasteur discovered it in 1848 while studying tartaric acid from wine making. He found two tartaric acids on the exact mirror image of the other like o
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
ur hands.
A solution of this compound derived from living things (specifically, wine lees) gave the chiral effect. The mystery was that tartaric acid derived by chemical synthesis had no such effect, even though its elemental composition was the same. It only worked with living, organic compounds.
For a young scientist (he was only about 2
A solution of this compound derived from living things (specifically, wine lees) gave the chiral effect. The mystery was that tartaric acid derived by chemical synthesis had no such effect, even though its elemental composition was the same. It only worked with living, organic compounds.
For a young scientist (he was only about 2
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
6 at that time) this first demonstration of chiral molecules was quite an achievement, but of course Pasteur then went on to his more famous work in the field of biology/medicine.
So, if it’s really not so new, why haven't we heard of this before? Well, nowadays chirality is the fastest growing investment by drug companies. So we’re sure to
So, if it’s really not so new, why haven't we heard of this before? Well, nowadays chirality is the fastest growing investment by drug companies. So we’re sure to
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
hear much more of it. The Dark Ages of medical science are coming to a close. You will now hear more about chiral technology processing.
So, getting back to skin care, if we understand some basic principles it will help us target our skin health needs.
The bottom line is that there are two basic layers of skin, the Epidermis and the Dermis.
So, getting back to skin care, if we understand some basic principles it will help us target our skin health needs.
The bottom line is that there are two basic layers of skin, the Epidermis and the Dermis.
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
These two layers, though separate, work as one system. The Epidermis serves as a barrier to the outside and must keep out sunlight, insects, germs, heat, cold, dirt and gases. At the same time it must withhold water, blood, minerals, vitamins, hormones and proteins. The Dermis must provide for body regulation of heat by the controlling of sw
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
eat evaporation and dermal blood flow. The skin must provide a system to allow the replacement of the outer cells lost to the environment and the Dermis must also serve as a vast waste disposal system of many toxic body substances.
Chiral technology allows for a product that is better than “natural” because it separates the molecules, allowi
Chiral technology allows for a product that is better than “natural” because it separates the molecules, allowi
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ng us to remove the undesirable side of the molecule and use only the desirable one.
Chirally correct ingredients thus have the ability to deliver outstanding results. Scientists have established that chirally correct molecules determine how, or even if, a particular ingredient will be effective. Therefore, in order for a product to be most
Chirally correct ingredients thus have the ability to deliver outstanding results. Scientists have established that chirally correct molecules determine how, or even if, a particular ingredient will be effective. Therefore, in order for a product to be most
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
effective, its ingredients must be chirally correct. Only chirally correct ingredients can restore chiral purity and alignment on a molecular level, and therefore, on a cellular level. Chirally correct fresh ingredients deliver nutrients deep into the cell's structure, nutrients that your skin can not only recognize, but use.
Chiral technolo
Chiral technolo
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
gy used in the development of skin care products ensures the delivery of ingredients to skin receptors. This means that the absorption of nutrients is not inhibited by the incorrect orientation of the active ingredients. Such mal-orientation, found in most skin care products, not only renders the product ineffective, it is often the cause of
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
irritation and other negative side effects. Since increased absorption of the proper ingredients is especially important when dealing with aged, sun damaged, acne, and sensitive skin, it is paramount to offer ingredients in a form that is easily absorbed, recognized, and utilized by the skin to restore the skin's integrity and immune function
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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