E-Articles - Health and Fitness

Psoriasis is a chronic skin condition which millions of people suffer from each year. Many people fear psoriasis when they see it, but it's not con

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

tagious in any way. In fact, it's thought to be caused by the body's own immune system.

If some big event happens to the body such as an injury, s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

evere illness, or even stress, people with psoriasis can have a flare up. The body's immune system will start generating new skin at much faster ra

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tes than normal, and this creates pile ups of extra skin on the surface. These pile ups are called psoriasis plaques or patches, and they are most

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

often seen on the elbows, knees or scalp. The plaques are usually made up of very thick white skin accumulations, which can be quite dry and itchy.

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

The patches often have white or silvery skin pieces flake off of them as well.

Modern medical specialists do not feel there are any cures for pso

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

riasis itself, but herbal remedy specialists feel there are. And most of the herbal remedies for psoriasis involve cleansing, toning and healing th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

e liver and colon.

The liver is the primary organ in the human body which filters out toxins and harmful materials from our body. It sends this in

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the form of bile to the gall bladder, which then sends it on to the colon as waste. The solid waste in the colon is then moved through the entire

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

length - about five to six feet - and expelled as stool through the bowels.

The colon is a much more important organ in the body than most people

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

realize though. It not only spans five to six feet in length, it is also connected to every other part of our body through nerve endings. So if som

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ething is wrong in the colon, many other parts of the body can suffer for it.

The colon can get backed up and stagnated easily too, for anyone who

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

does not eat a proper diet. And when the colon gets stagnated, the waste material can leak toxic poisons back into the blood stream, and contamina

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

te other major organs.

So the primary herbal remedies for psoriasis involve cleansing the colon, liver, and gall bladder, plus helping those organ

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s to heal and repair if they are damaged, so they can operate more efficiently in the future.

Herbal remedies for psoriasis often involve taking h

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

erbal supplements which are known to be excellent liver and colon herbs. Here are the top three:

1. Slippery Elm - This is an excellent colon herb

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

which helps cleanse, tone and heal. It will normalize stools too, so if any of the backed up waste in the colon has become dried out and hard, it

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

can help soften that waste so it can be moved out of your system normally.

2. Dandelion - This is an excellent liver cleansing and toning herb. It

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

helps the liver cleanse, plus heal and repair if needed. It also stimulates the liver to produce more bile, which helps move backed up toxins out

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

of your body more quickly.

3. Cascara Sagrada - This herb is a natural laxative which will help your colon cleanse old waste materials and toxins.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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