E-Articles - Health and Fitness

It's spring and all the new growth that Mother Earth has is beginning to appear. There are so many plants growing right next to our doorstep and are often

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

labeled as 'weeds' that have healing gifts to share. For many years these 'weeds' have been used for folk medicine and healing remedies that are very easy

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

to make. One of the most common plants you will find growing throughout your yard and just about anywhere is plantain. Its broad leaf has a curving vertica

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

l ridge and is oval in shape. You may find a slender stalk growing from the center of the plant during flowering. By using plantain leaves to make a poulti

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ce or herbal salve you can make use of a common plant that is so plentiful around us. Making your own plantain herb salve is easy and economical. You will

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

need the following ingredients:

Fresh cleaned plantain leaves

Olive oil and/or safflower oil

bees wax

large jar (pint or your choice) with lid

small b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

aby food jars or other wide mouthed jars

There are different methods of creating salve but we are going to use a slow process from the folk tradition. The

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

first thing to do is locate your plantain and gather your leaves when they are dry. You will need enough leaves to fill the large jar. Next clean the dirt

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

from the leaves and allow them to air dry for a few hours to reduce the moisture content. Then when you are ready to begin you will chop the plantain leav

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

es to release the essence inside the leaf and place them into your large jar until full. Gently warm enough oil in a pan on your stove top to cover the lea

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

es completely plus some. The oil should not be boiling hot but warm. Then carefully pour the oil into the jar completely covering the plant plus an inch or

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

so more. You can use a wooden spoon to push the plant down if needed. Cover with some waxed paper and the lid and allow to sit for up to a few weeks or so

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

. WATCH FOR MOLD so you do not lose your oil. It is good to give it a gentle nudge daily by taking the jar in your hands and swirling the contents around.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

When you are ready to make your salve pour the oil through a strainer or cheesecloth. Squeeze all the oil out of the plant material and save the leaves fo

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

r compost. Now you will heat the oil slowly and keep stirring gently with a wooden spoon while adding your bees wax until it reaches the consistency that y

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ou like. This can be tested by dipping a spoon or stick in and placing it in the freezer until it hardens. Normally you will use about one and a half ounce

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s of bees wax for a pint of oil, but can use more if you desire a firmer salve. When it is the desired texture the mixture is ready to pour into the small

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

jars. Allow it to cool and voila you have a few wonderful jars of plantain herb salve.

This salve is great for insect bites, stings, shallow scrapes, baby

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

bums, dry skin and much more. Oh, and if you are ever outdoors and do not have access to your salve just reach for a plantain leaf, macerate it, mix it wi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

th some saliva (or chew it like I do, just make sure it IS plantain) and you have a handy poultice for a bite, sting or?!

Enjoy your journey with plantain

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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A wedding takes an enormous amount of time and money. From the hall to the dress, the flowers, the cake, invitations, food etc., it is wise to save where you can. You may not want to cut corners with your dress but you can save a lot of money doing your own flowers.

Fighting off Bad Breath is the sane thing to do while pursuing your goals. Otherwise you get to find out how much people already know of your mouth breath status if you finally achieve your dreams. At other times, it outrightly hampers your progress and makes you socially incompetent. Bad Breath can cause you too much in your personal or professional relationships. Without much ado, let's quickly walk through the steps, the simple baby steps you need to take in order to fight off Bad Breath.

One of the many benefits of making your own juices is the freedom that you get from store bought prices and formulas. With a few exceptions many store bought juices are often created with additives and artificial ingredients and cost you more than the fruit would normally. The Jack Lalanne power juicer is a product that offers not only the opportunity to bypass those pricey in-store options but to have fun while doing so.

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