E-Articles - Health and Fitness

Flawless skin, refined texture, and the softness you would love to touch—these are the constant promises and benefits of Anti Aging Creams we find in cosmetics department stores, today. Women are consta

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ntly in search for the best products in the market and online, which could provide them with the rejuvenating miracle they have always been looking for in various Anti Aging products. Whether the produc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is imported or locally made, whether it is pricey or affordable, as long as it can fulfill the nagging need in most women to retain their youth, cash registers would always have a field day in stores.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

If we take a look at the shelf giants today like Biotherm, L’Oreal, Zirh, among others, they are known for the “special” ingredients they contain—the ones guaranteed to offer the best results overnight

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

or for a considerable length of time depending on skin type and the individual’s beauty and anti-aging demands. However, there are only two kinds of anti-aging cream in the market today regardless what

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

is stated on their labels. It is time to define the difference between naturally and chemically manufactured products. Yes, we set our sights on the benefits, but the ingredients worth a look, too.

Be

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

uty products always carry tag lines which titillates the senses – everyone wants to become beautiful. Beauty always captures the world, so they say, in fact, every famous man or woman in history always

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

has another man or woman behind who influenced the course of their fate. What we don’t see beneath the surface of elegant plastic container and within plastic cream bottles are beauty ingredients that

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

may be harmful.

Let us separate the common setting of a grocery shelf into two: natural skin creams from artificial creams. Although the packaging will tell us that they offer common benefits, the pack

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

aging will never tell us if they have side effects, and most importantly what they truly contain.

Let us take a bottle of natural anti aging cream for an example. The product’s contents may come from l

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

aves like natural Aloe Vera, Asian Papaya, fruit and vegetable essence, and other naturally acquired substances. Evaluating the ingredients of this cream, we will surely agree to one thought: there are

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

less chances of having side effects due to the natural aspects of the product.

Natural anti aging creams have always been less suspect

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

d to cause cancer and skin problems. Irritation and allergies have less chances of occurring due to the compatibility of natural essence to most skin types. Natural anti aging creams are known for their

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

special ability of adapting to different skin types without causing irritations, wounds, and rashes. Aside from being just the “friendly type” of cream, natural anti aging creams can produce the same n

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

noparticles which artificial items are injected with. These nano-particles, also termed microenscapulation, make the natural ingredients easier to be absorbed by the skin.

Unfortunately, not all natura

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

l creams last long enough to provide the user their best results. Natural creams are easily spoiled unless injected with preservatives; but opting for that would mean losing the natural essence of the p

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

oduct.

Let us now pick up a household name from the shelf were artificial creams belong to. If we view them closely, they may contain uncommon ingredients. They either contain most of the laboratory-in

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

fused ingredients or they are plainly too artificial thus unsafe for usage. Also known as artificial anti aging creams, these products contain unnatural peptides, Vitamin A or retina-A, Alph-Lipoic Acid

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

and Hyaluronic Acid or DMAE. These products are possible factors for skin rashes when used onto the wrong skin type, and worse, they could be the very sources of skin cancer and other skin abnormalitie

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s

As a cosmetics user, you are always open to two options: go artificial or go natural, but for the choice of safety and for the choice of receiving par benefits, going natural would be the best option

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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