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Don’t you dream of having great looking skin? Our skin is a reflection of ourselves. Great looking skin is not just about good genes. It needs to be cleansed, moisturized and protected

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

with a reliable and effective skincare regimen.

As we get older, there can be significant changes in the way our skin looks. This isn’t hard to imagine. Our skin’s declining metabolism

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

, coupled with the presence of free radicals, environmental pollution and sun exposure wears down our skin. The epidermis(outer layer of skin) begins to lose its ability to retain moist

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ure and thus becomes dry. As collagen diminishes, skin is subjected to wrinkling and sagging. The damage to the dermis (inner layer of skin) from the effects of sun exposure over the de

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

cades also becomes visible. We begin to see evidence of ageing in the appearance of fine lines and wrinkles, dry and rough skin texture, uneven skin tone, skin dullness, visible pores,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

age spots and lack of firmness.

To solve the above problems, a skin care product should allow your skin to experience the process of re-construction and re-conditioning in a simple, sa

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

fe & speedy way. It should be infused with skin-loving vitamins and minerals to give your skin a whitening and rejuvenating boost that takes years aways from your complexion.

Such a pr

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

duct should have an anti-aging formula that works on your skin from within. This is very different from common skin care product which works only on the skin surface. It is likely to be

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

a pharmaceutical grade product, that have highly effective ingredients which can penetrate the dermis layer to remove dead cells and bring out new skin cells below to rejuvenate your s

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

kin. This is known as the skin “re-construction” period, where light peeling and redness of the skin may be seen as this process accelerates the growth of healthy cells.

You will be am

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

azed when skin problems such as acne, pigmentation, scarring, wrinkles and premature aging fade away to reveal fresh, new and healthy skin! After that, the product should be able to mai

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ntain and nurtures your renewed skin, giving it the radiance your complexion deserves.

You will love the feeling of seeing improvement of your skin day by day. You will love yourself m

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ore. You will love to look at yourself inside the mirror.

The product should also delivers the 3 major antioxidants, Vitamins (A,C & E) deep into the lowest layers of the skin, helping

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

to restore and build up healthy skin cells from within. The infusion of Vitamins A, C and E not only protects the skin from the harmful effects of free radicals and the elements. They

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

efine the skin’s texture, making it supple and radiant.

Vitamin A

Lack of vitamin A causes the skin to become dry, rough and lacklustre. When applied directly to the skin, it removes

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

wrinkles and pigmentation caused by sun exposure. Vitamin A also promotes cell metabolism and blood circulation, giving your skin a healthy glow.

Vitamin C

Not only does vitamin C pro

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tect the skin bu increasing its moisture balance, it has a rejuvenating effect. It is proficient in skin whitening and fading of pigmentation and dark spots, inhibiting the formation of

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

melanin concentration. Vitamin C also assists the skin in the production of collagen, which helps skin to maintain its firmness and elasticity.

Vitamin E

By preventing the oxidation

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

of lipids, Vitamin E effectively protects the skin from the assault of free radicals. This helps to speed up healing and maintain skin’s natural elasticity, adding resilience to it.

Wi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

th all these in mind, your skin will have a healthy and lustrous appearance you’ve always dream of. Your skin loves attention, so pamper it and see the youthful, glowing results forever

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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