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E-Articles - Direct & Indirect Immune Enhancing Properties of Aloe Vera and Colloidal Silver
Aloe vera is a succulent plant well-known for producing a thin, clear gel-like substance that provides soothing relief for common skin irritations. But another substance, known as aloe vera latex, can also be obtained from the inner leaf skin. Aloe vera products include aloe vera gels, l
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
otions and soaps, which can be applied topically to cuts, scrapes, burns or insect bites for gentle relief. Aloe vera supplements are also available in both liquid and capsule form.
Aloe vera has long been acclaimed the "healing plant". It is the most widely used plant for skin applicat
Aloe vera has long been acclaimed the "healing plant". It is the most widely used plant for skin applicat
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
ons in history, assisting with natural healing and skin regeneration. Aloe vera is a stem less perennial evergreen plant belonging to the lily family. It is thought to have originated from northern Africa and the Arabian Peninsula. Today it is widely cultivated in southern Texas, Mexico,
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
and coastal Venezuela. Aloe gel is a mucilaginous gel obtained from splitting open the center of the succulent leathery leaves of the aloe vera plant. It is this gel inside the leaves, which is aloe vera's lifeblood that is rich in many nutrients and water. It is the storehouse of over 1
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
0 minerals, enzymes, vitamins, lipids, amino acids and other active compounds - some of which are exclusive to aloe vera, that give this plant a wide array of natural health applications, which often seem too good to be true. The gel from the inner core of the leaf is rich in glucomannan
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
s and other polysaccharides.
Aloe Vera has been recognized for centuries for its remarkable health-enhancing properties. Although known specifically for external application to the skin, aloe juice is now widely used to help a variety of conditions. Also, the cold processed whole aloe v
Aloe Vera has been recognized for centuries for its remarkable health-enhancing properties. Although known specifically for external application to the skin, aloe juice is now widely used to help a variety of conditions. Also, the cold processed whole aloe v
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
ra leaf has so many essential properties. It is nutritional and provides vitamins, minerals, amino acids and enzymes. It acts as an anti-inflammatory agent. It hastens wound-healing by enhancing cell proliferation. It breaks down and digests dead tissue, including acne. It anesthetizes t
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ssue, relieving pain associated with joints and sore muscles. It is antipruritic as it stops itching. It is antipyretic as it reduces the heat of sores. It is claimed to have anti cancer properties. It is anti infection and it aids in digestion. It speeds healing, tensile strength and re
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
air of damaged skin. It also holds moisture and adds flexibility to retard aging.
The anti-cancer activity of aloe indicates that its action is through stimulation of the scavenging white blood cells of the immune system. Research has proven that aloe vera prevents suppression of the sk
The anti-cancer activity of aloe indicates that its action is through stimulation of the scavenging white blood cells of the immune system. Research has proven that aloe vera prevents suppression of the sk
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
in's immune system. It is such findings which made scientist believe about the immune enhancing properties of aloe vera plant. New experiments have been performed in this direction and results are amazing. It is established by these experiments that bio-protectively processed aloe vera i
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
both directly and indirectly immune enhancing. Aloe vera is found to contain following indirect immune enhancing properties:
It is antioxidant. It helps in better absorption of nutrients. It leads to digestive system improvement. It also helps in digestive and elimination cleansing. Th
It is antioxidant. It helps in better absorption of nutrients. It leads to digestive system improvement. It also helps in digestive and elimination cleansing. Th
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
se properties do support the immune system to be able to work better in that they take some of the burden off it and improve nutritional absorption but these are not the aloe properties that "directly" improve immune system functioning.
The direct immune enhancing properties of aloe ver
The direct immune enhancing properties of aloe ver
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
directly improve immune system functioning. The fresh aloe vera plant is unique in that it contains the full range of all sizes of polysaccharides and is the most concentrated plant source of the largest ones known, the beta-linked glucomannans (also known as Acemannan, acetylated polym
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
annose, mucopoly-saccharides, MPS, Aloe polysaccharides). These very large and complex, intricate polysaccharides found in fresh aloe are responsible for the profound and direct immune enhancing properties demonstrated by scientific research. These polysaccharides have been shown to be d
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
rectly immune enhancing by being able to survive the digestive process. It is taken up whole, intact into the lymph system and it stimulates macrophages by fitting their receptor site. It is this property of being able to stimulate macrophages that make these polysaccharides profoundly i
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
mune enhancing in every way because the macrophages are the main immune cells that regulate the workings of the entire immune system. The macrophages have a myriad of functions which include engulfing foreign bodies and releasing growth factor (which stimulates tissue production). It als
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
simulates cells and all functions of the entire immune and repair system including immune system modulation which is the regulation of the immune response (stimulating it and shutting it down). It is also responsible for regulating the inflammation process (increase and decrease), relea
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
sing factors that tell the immune cells where to go, and releasing factors that stimulate the other immune cells to release their antibodies when and where needed. These polysaccharides are manufactured by our bodies only until puberty and are difficult to find from food sources. It has
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
een recently discovered that aloe is the most concentrated plant source of these mucopolysaccharides (beta-glucomannans).
It is no wonder that aloe vera is being used in so many cosmetic products, soap being one of them. The aloe vera soap contains all of its direct and indirect immune
It is no wonder that aloe vera is being used in so many cosmetic products, soap being one of them. The aloe vera soap contains all of its direct and indirect immune
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
nhancing properties. These soaps rejuvenate the skin and prevent it from infections. Apart from being a good cleanser, such soaps are known for its health reasons too. Dermatologists all over the world have accepted the quality of these soaps and they are suggesting them to their clients
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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