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Silver is one of the most universal antibiotic substances. When administered in the colloidal form, it is for all practical purposes, non-toxic. Silver has been proven to be useful against hundreds of infectious conditions. Although the exact mechanism for the proven antimicrobia

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

l effects of colloidal silver is unknown, the most accepted theory is that colloidal silver disables the specific enzyme that many forms of bacteria, viruses and fungi utilize for their metabolism.

Colloidal silver is the result of an electromagnetic process that pulls microscop

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

c particles from a larger piece of silver into a liquid, such as water. These microscopic particles can more easily penetrate and travel throughout the body. Colloidal works as a catalyst, disabling the enzyme that all one-celled bacteria fungi and viruses use for their oxygen me

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

abolism. In short, the bad guys suffocate. Unlike with antibiotics, resistant strains have never been known to develop. In fact, antibiotics are only effective against perhaps a dozen forms of bacteria and fungi, but never viruses. Because no known disease-causing organism can li

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e in the presence of even minute traces of chemical element metallic silver, colloidal silver is effective against more than 650 different disease-causing pathogens.

The above discussed anti bacterial properties of colloidal silver was found by scientists in early 1900's. Howeve

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

, discovery of antibiotics led to almost erosion of colloidal silver. The comeback of colloidal silver in medicine began in the 1970's. The late Dr. Carl Moyer, chairman of Washington University's Department of Surgery, received a grant to develop better treatments for burn victi

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s. Dr. Margraf, the chief biochemist, worked with Dr. Moyer and other surgeons to find an antiseptic strong enough, yet safe enough, to use over large areas of the body. As a result of their efforts, and that of other researchers, hundreds of important new medical uses for silver

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

were found. Another fact favoring colloidal silver has been the recent revolution in the technology of colloidal silver production. It is possible now to produce far more superior silver colloids such as Sovereign Silver, at a far more reasonable cost than previously possible. T

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

is revolution in silver colloid could well see science go full circle, as antibiotics become more and more out of reach and unable to cope with the new range of super bugs such as MRSA that are sweeping the globe and eventually being replaced by their own predecessor, silver coll

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

id.

The future of colloidal silver is bright. Hopefully with today's technological advances, we can avoid the past mistakes and benefit from its wide range of advantages to prevent and treat infectious disorders. Although reports on the use of colloidal silver have spanned the p

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

st 100 years, research relating to its recent use is limited. However, through a growing number of physicians, dentists, veterinarians, nutritionists and satisfied users, information regarding the modern day uses of colloidal silver is mounting.

One of the areas of interest has

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

een relevance of colloidal silver in treatment of AIDS. In a groundbreaking study, the Journal of Nanotechnology has published a study that found silver nanoparticles kills HIV-1 and is likely to kill virtually any other virus. An obscure but crucial discovery was made at the Bio

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

hemistry Unit of Upjohn Laboratories in 1991. Among a number of metal ions tested, Zn2+ (zinc), Cn2+ (copper), and Ag1+ (silver) were found to be the most effective inhibitors of renin and the HIV protease. This was the first report that silver is a highly effective protease inhi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

itor. Over the following years, this same discovery would be made several times. A year later, this same discovery was made at the University Medical Center in Geneva, Switzerland. As per him, Metal-binding proteins are important components of retroviruses such as human immunod

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

eficiency virus (HIV). Therefore, metals could be used as antiviral agents. Silver is a highly active bactericidal metal with little toxicity for humans. These findings have opened an important avenue for research. A lot of research is being conducted in this direction and though

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

a concrete result is not yet available, hopefully in near future, colloidal silver may prove to be an essential part in treatment of AIDS.

Colloidal silver will also be used extensively in skin care industry in coming years. More and more people are accepting the virtues of coll

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

idal silver and its usefulness for healthy skin. It has opened doors for usage of colloidal silver in cosmetic products. The cosmetic industry is growing at fast pace and it is quite appropriate time for colloidal silver to be part of it. Colloidal silver has been already used as

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a main ingredient in soap manufacturing, which has proven to be a big success. The colloidal silver soap has proven itself in curing various skin disorders like acne, skin rashes, athlete’s foot etc. It has also been found as rejuvenating to the human skin. It is also being used

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

n lotion, shampoo etc. In coming years, it may find its usage in other household products as well.

Scientists are also experimenting about the use of colloidal silver in the field of treatment of deadly diseases like cancer etc. The way things are progressing, it can be said tha

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the days are not far when colloidal silver may prove to be a cure for cancer too.

Overall, it seems that the effective and safe use of colloidal silver in the treatment of dozens of common infectious disorders is only limited by the imagination and creativity of those afflicted

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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